Results 61 to 70 of about 971,459 (303)
Resources such as water taken up by plants can be released into soils through hydraulic redistribution and can also be translocated by clonal integration within a plant clonal network.
Xuehua eYe +10 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
A theory for the expression of a population's response to density-independent gradients of environmental factors is derived for the case of asexuality. It is shown that the environmental tolerance of a genotype is a function of at least four parameters ...
Gabriel, Wilfried, Lynch, Michael
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Dynamics of extinction in coupled populations of the flour beetle Tribolium castaneum
In this study we analyzed the effect of migration on the persistence time of coupled local populations of Tribolium in different environments. Four treatments were set up to compare different levels of environmental heterogeneity.
W. A. C. Godoy, M. I. S. Costa
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The effect of environmental heterogeneity on RPW8-mediated resistance to powdery mildews in Arabidopsis thaliana [PDF]
Background and Aims: The biotic and abiotic environment of interacting hosts and parasites may vary considerably over small spatial and temporal scales. It is essential to understand how different environments affect host disease resistance because this ...
Agrios +70 more
core +1 more source
Transnational environmental agreements with heterogeneous actors [PDF]
This paper explores transnational environmental agreements on climate change. As the Paris agreement of 2015 contains no binding emission reduction targets for nation states, understanding other forms of cooperation as complements to the United Nations Framework Convention on Climate Change (UNFCCC) process becomes increasingly important.
Hagen, Achim +2 more
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

