Results 51 to 60 of about 971,459 (303)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Seasonal and habitat structure of an anuran assemblage in a semideciduous forest area in Southeast Brazil [PDF]

Anais da Academia Brasileira de Ciências
In this study, we evaluated the reproductive activity and the temporal and spatial distributions of anuran assemblages in three environments within a semideciduous forest in Southeast Brazil, located at Municipality of Barão de Monte Alto, State of Minas
ELVIS A. PEREIRA, MATHEUS O. NEVES, JOSÉ LUIZ M.M. SUGAI, RENATO N. FEIO, DIEGO J. SANTANA   +4 more
doaj   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The relative importance of regional and local factors in shaping zooplankton diversity in high-altitude tropical shallow lakes

Journal of Freshwater Ecology, 2020
In Brazil, although, high-altitude shallow lakes comprise large parts of conservation units and are considered highly important environments for biodiversity studies, little is known about the factors that regulate the zooplankton community.
Eneida Maria Eskinazi-Sant’Anna, Gleice de Souza Santos, Natacha Jordânia da Silva Alves, Lorena Aparecida Fortes Brito, Mariângela Garcia Praça Leite   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Uncertainty, Learning and Heterogeneity in International Environmental Agreements [PDF]

Environmental and Resource Economics, 2011
This paper concerns the formation of International Environmental Agreements under uncertainty about environmental damage with different models of learning (complete learning, partial learning or no learning). The results of the existing literature are generally pessimistic: the possibility of either complete or partial learning generally reduces the ...
Kohlstad, Charles, Ulph, Alistair
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effects of Soil Nutrient Heterogeneity on the Growth and Invasion Success of Alien Plants: A Multi-Species Study

Frontiers in Ecology and Evolution, 2021
Spatial heterogeneity in soil nutrient availability can influence performance of invasive plant species under competition-free environments. However, little was known about whether invasive plants perform better under heterogeneous than under homogeneous
Fang-Lei Gao, Fang-Lei Gao, Qiao-Sheng He, Yi-Dan Zhang, Jia-Hui Hou, Fei-Hai Yu   +5 more
doaj   +1 more source

Inherited and Environmental Factors Influence Human Monocyte Heterogeneity [PDF]

Frontiers in Immunology, 2019
Blood monocytes develop in the bone marrow before being released into the peripheral circulation. The circulating monocyte pool is composed of multiple subsets, each with specialized functions. These cells are recruited to repopulate resident monocyte-derived cells in the periphery and also to sites of injury.
Patel, AA, Yona, S
openaire   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source