Results 111 to 120 of about 795,117 (293)

Environmental News You Can Use [PDF]

open access: yes, 2007
Monthly newsletter of the Texas Commission on Environmental Quality containing information on environmental topics of interest to the general public and other groups including municipalities, businesses, corporate environmental managers, school teachers,
Texas Commission on Environmental Quality. Small Business and Environmental Assistance Division.
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Reflections: Environmental History in the Era of COVID-19. [PDF]

open access: yesEnviron Hist Durh N C, 2020
Alagona P   +19 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Rochester's rivers, lake, and waste: teaching local environmental history using water case studies. [PDF]

open access: yesWater Hist, 2020
Chomiak K   +5 more
europepmc   +1 more source

Ice Blink: Navigating Northern Environmental History

open access: yes, 2017
Northern Canada's distinctive landscapes, its complex social relations and the contested place of the North in contemporary political, military, scientific and economic affairs have fueled recent scholarly discussion.
Bocking, Stephen, Martin, Brad
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

La bête en ses jardins

open access: yesProjets de Paysage
Through an analysis of approximately five hundred letters exchanged between 1662 and 1686 by the people involved in the building of the gardens of Chantilly at the time of Le Nôtre, this article demonstrates the importance of observation in the ...
Serge Briffaud, Emmanuelle Heaulmé
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Extreme Spaces as Encounters: Images, Environments, and Otherness

open access: yesArts
Spaces labeled as ‘extreme’ have long fueled the imagination of those who sought to explore, conquer, and represent them. Framed in colonial narratives as terra incognita or finis terrae, these regions generated diverse forms of textual and visual ...
Maria Berbara   +2 more
doaj   +1 more source

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