Results 111 to 120 of about 13,095,443 (310)
Obesogenic effects of perinatal bisphenol AF exposure on prepubertal male offspring rats
Shanghai yufang yixueObjectiveTo investigate the disruptive effects of perinatal exposure to the environmental endocrine disruptor bisphenol AF (BPAF) on hepatic lipid metabolism in prepubertal (postnatal day 21, PND21) male offspring rats, and to provide scientific evidence
LIU Xi +5 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
CONCEPTUALIZING AND QUANTIFYING THE ENVIRONMENTAL IMPACTS OF BIOLOGICAL PRODUCTION SYSTEMS
, 2014 Increasing the amount of food produced while simultaneously reducing the environmental impacts of agriculture is one of the most pressing challenges facing humanity.
McGrath, Keegan
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Biodiversity in environmental assessment : current practice and tools for prediction
, 2006 Habitat loss and fragmentation are major threats to biodiversity. Environmental impact assessment and strategic environmental assessment are essential instruments used in physical planning to address such problems. Yet there are no well-developed methods
Gontier, Mikael, +2 more
core +1 more source
Removal mechanism of decabromodiphenyl ether in soil by Cu/Fe nanoparticles
Hygiene and Environmental Health AdvancesDecabromodiphenyl ether (BDE-209), a widely used and environmentally significant legacy brominated flame retardant, is frequently found in farmland soil near electronic waste disposal sites and manufacturing facilities.
Siyuan Ling, Ying Han, Shuangqing Hu
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Effectiveness of environmental offsets in environmental impact assessment: Practitioner perspective from Western Australia [PDF]
, 2007 Environmental offsets are positive mitigation measures implemented during environmental impact assessment (EIA) approvals to compensate for unavoidable negative environmental actions.
Hayes, N., Morrison-Saunders, A.
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Proximity Lens on Structural Collaborations: A Method for Impact Assessment
This resource provides a description of ‘proximities’ in impact assessment, building on Boschma (2005) and Knoben & Oerlemans (2006). Proximity dimensions provide a lens to identify and highlight the conditions that enable successful cooperation and ...
Evaluating Societal Impact
core +1 more source