Results 121 to 130 of about 13,095,443 (310)

Probing the binding stability of organic UV filters to human SLC transporters using AlphaFold and molecular dynamics simulations

Scientific Reports
The ubiquitous presence of organic ultraviolet filters (UVFs) in environmental and human, driven by their heavy usage in personal care formulations, has raised significant concern.
Ruikai Xing, Zhongquan Jiang, Tianyi Wei, Jiale Chen, Lijun Zhang, Shuangqing Hu, Zhemin Shen, Tao Yuan   +7 more
doaj   +1 more source

Nationwide distribution of perfluoroalkyl ether carboxylic acids in Chinese diets: An emerging concern

Environment International
With the phase-out of perfluorooctanoic acid (PFOA) and its replacement by perfluoroalkyl ether carboxylic acids (PFECAs), there is a potential for increased exposure to various new PFECAs among the general population in China.
Fengfeng Dong, Haijun Zhang, Nan Sheng, Jianglin Hu, Jiayin Dai, Yitao Pan   +5 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Impact Strategy Development: Questions Bank and Interview Guide

The tool ‘Impact Strategy Development: Questions Bank and Interview Guide’ consists of (1) a three step interview guide and (2) an Excel file with a questions bank to use and tailor for your interviews or other methods for engaging with your community ...
Evaluating Societal Impact
core   +1 more source

Impact methods to predict and assess contributions of technology (IMPACT): Final report [PDF]

, 2000
Metadata only recordThis report covers research done for the USAID Office of Agriculture and Food Security of the Center for Economic Growth and Agriculture (Global Bureau).
Texas A&M University
core  

CircRNA_1156 Attenuates Neodymium Nitrate-Induced Hepatocyte Ferroptosis by Inhibiting the ACSL4/PKCβII Signaling Pathway

Antioxidants
Ferroptosis, a form of regulated cell death driven by lipid peroxidation, has been implicated in the pathogenesis of liver diseases. This study investigates the role of circRNA_1156 in neodymium nitrate (Nd(NO3)3)-induced hepatocyte ferroptosis.
Ning Wang, Jing Leng, Jing Xu, Kelei Qian, Zhiqing Zheng, Gonghua Tao, Ping Xiao, Xinyu Hong   +7 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Thinking About my Impact and Engagement: A Worksheet

What does making positive societal impact mean to you? How do you map current and potential partners and beneficiaries? How to align your work to their needs? This workshop package offers a brief printable worksheet with accompanying presentation slides,
Evaluating Societal Impact
core   +1 more source

Neodymium Nitrate Suppresses Malignant Phenotypes in Hep-G2 Cells by Targeting Nrf2 to Inhibit EMT and Induce Ferroptosis

Toxics
Hepatocellular carcinoma (HCC) is characterized by a poor prognosis, largely driven by metastasis and therapy resistance, processes closely linked to epithelial–mesenchymal transition (EMT) and ferroptosis.
Jing Leng, Ning Wang, Ping Xiao, Xinyu Hong, Song Yu   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source