Results 121 to 130 of about 5,123,940 (303)

A Transnational Perspective on Extending NEPA: The Convention on Environmental Impact on Assessment in a Transboundary Context [PDF]

open access: yes, 1995
Introduction In recent years, the potential adverse impacts of transboundary pollution have received heightened attention both domestically and abroad.
Battle, Laura Carlan
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Image-Based Crack Detection Algorithm for Reinforced Concrete Water Tank Based on Improved YOLOv5s

open access: yesBuildings
Image-based detection of concrete water tank damage in mining areas holds promise for practical applications. However, current deep learning-based detection algorithms often face challenges in balancing accuracy with computational complexity for real ...
Yanmei Ma   +4 more
doaj   +1 more source

Environmental impact assessment of the manufacturing of a commercial aircraft [PDF]

open access: yes, 2013
This paper documents the methodology and presents the results of a comprehensive LCA study of an Airbus A320 commercial airliner to determine the relative environmental impact of its manufacturing phase.
Asproulis, Nikolaos   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

AKTive Food: Semantic Web based knowledge conduits for the Organic Food Industry [PDF]

open access: yes, 2005
We present a vision and a proposal for using Semantic Web technologies in the organic food industry. This is a very knowledge intensive industry at every step from the producer, to the caterer or restauranteur, through to the consumer. There is a crucial
Brewster, Christopher   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Meteorological assessment of SRM exhaust products' environmental impact [PDF]

open access: yes
The environmental impact of solid rocket motor (SRM) exhaust products discharged into the free air stream upon the launching of space vehicles that depend upon SRM boosters to obtain large thrust was assessed.
Dingle, A. N.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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