Results 51 to 60 of about 13,095,443 (310)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Status of Solar Power Plant Sites Including First Grade Zones on Ecological and Natural Maps in South Korea [PDF]
Geo DataThis study collected and analyzed data registered in the Environmental Impact Assessment Information Support System for 1,321 solar power projects, whose environmental impact assessments and small-scale environmental impact assessments were completed in ...
Nanghee Kim +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
环境与职业医学BackgroundOccupational health places often involve complex dust samples characterized by diverse compositions and a lack of prior supplementary information.
Ruijie LIANG, Lingyi WEI, Chaoye SHEN
doaj +1 more source
Human displacements from Tropical Cyclone Idai attributable to climate change [PDF]
Natural Hazards and Earth System Sciences, 2023 Extreme weather events, such as tropical cyclones, often trigger population displacement. The frequency and intensity of tropical cyclones are affected by anthropogenic climate change. However, the effect of historical climate change on displacement risk
B. Mester +7 more
doaj
Environmental Impacts—Terrestrial Ecosystems [PDF]
, 2016 The chapter starts with a discussion of general patterns and processes in terrestrial ecosystems, including the impacts of climate change in relation to productivity, phenology, trophic matches and mismatches, range shifts and biodiversity. Climate impacts on specific ecosystem types—forests, grasslands, heathlands, and mires and peatlands—are then ...
Hölzel, N. +5 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Environmental Impacts—Lake Ecosystems [PDF]
, 2016 The North Sea region contains a vast number of lakes; from shallow, highly eutrophic water bodies in agricultural areas to deep, oligotrophic systems in pristine high-latitude or high-altitude areas. These freshwaters and the biota they contain are highly vulnerable to climate change.
Adrian, Rita +7 more
openaire +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source