Results 91 to 100 of about 2,735,682 (296)

Chemical carcinogenicity of neodymium nitrate in AML12 hepatocytes: Dose-response metabolomics and sensitive biomarker identification

open access: yesEcotoxicology and Environmental Safety
This study aims to investigate the chemical carcinogenic toxicity of neodymium nitrate (Nd(NO3)3) in mouse hepatocytes AML12 using dose-response metabolomics. Specifically, our objectives are to: Identify key metabolites that respond to Nd(NO3)3 exposure.
Ning Wang   +10 more
doaj   +1 more source

European Union environmental regulations and their potential impact on market access for Africa's exports [PDF]

open access: yes
international trade;impact assessment;European Union;Africa;access to markets;environmental protection;exports;international agreements;environmental ...
Mihyo, P.B.
core   +1 more source

Ozone Response to Aircraft Emissions: Sensitivity Studies with Two-dimensional Models [PDF]

open access: yes, 1992
Our first intercomparison/assessment of the effects of a proposed high-speed civil transport (HSCT) fleet on the stratosphere is presented. These model calculations should be considered more as sensitivity studies, primarily designed to serve the ...
Brasseur, G.   +9 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

VDAC1 Intervention Alleviates Bisphenol AF-Induced Succinate Metabolism Dysregulation and Inflammatory Responses

open access: yesPharmaceuticals
Background/Objectives: Bisphenol AF (BPAF) is a prevalent environmental contaminant with demonstrated metabolic and immunological toxicity. This study aimed to investigate whether VDAC1 (Voltage-Dependent Anion Channel 1) mediates BPAF-induced succinate ...
Xinyu Hong   +7 more
doaj   +1 more source

Regulation of Glyphosate-Resistant Sugar Beets: Challenges and Uncertainty [PDF]

open access: yes
Roundup Ready Sugar Beets, Regulation, Deregulation, Environmental Impact Statement, Environmental Assessment, Uncertainty, Agricultural and Food Policy, Crop Production/Industries, Q18, Q55, Q58,
Oeschger, Tara   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Environmental Impact Assessment

open access: yesJAPAN TAPPI JOURNAL, 2000
Environmental impact assessment “EIA” is a social system that prevent environment growing worse by taking measures to protect environment appropriately based on the results of investigations, forecasts and evaluations about various impacts of development before the project will be enforced.This system is applied to big projects, therefore up to now ...
openaire   +2 more sources

Noise impact on wildlife: An environmental impact assessment [PDF]

open access: yes
Various biological effects of noise on animals are discussed and a systematic approach for an impact assessment is developed.
Bender, A.
core   +1 more source

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