Results 71 to 80 of about 703,328 (308)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The Influence of EIA Approval Conditions on Environmental Practices

, 2002
The theme of the conference was to reflect on the role of impact assessment in the process of decision making and managing a business. He or she who sees an IA as a "societal permit" will be in for a disillusion. Such a permit will only be accessible via
Dik, H., Morrison-Saunders, A.
core  

Occurrence Status of Legally Protected Species in Environmental Impact Assessment Reports [PDF]

Geo Data
In environmental impact assessments, the presence or absence of legally protected species is one of the important considerations when evaluating site feasibility.
Joohyun Seo, Hae-Ran Kim, Minho Chang, Nanghee Kim, Jinjoo Na, HaEun Lee, Jaegyu Cha, Jungkwon Kim   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Temporal variation in discharge coefficients of non-point source pollution and its determinants in river-network areas in a plain

Guan'gai paishui xuebao
【Objective】 Discharge coefficient is a coefficient describing the discharge of non-point source pollution to water bodies. It is affected by many biotic and abiotic factors.
DUANMU Jiayao, CHEN Cheng, CHEN Xiaohua, SHEN Genxiang, ZHANG Min, GUO Chunxia, WANG Zhenqi, BAI Yujie, LING Zhixiong, CAO Guomin   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Environmental Impact Assessment in the Bay of Bengal sub region in South Asia

, 2008
The environmental problems faced by the countries of the Bay of Bengal Sub region in South Asia (hereinafter the region) are significant but they are far from being managed in a sustainable manner.
Hassan, Daud, Hassan, D
core   +1 more source

Effects of inhalation of polyhexamethylene guanidine disinfectant aerosol on immune organs and immune cells in mice

环境与职业医学
BackgroundThe respiratory toxicity of inhaled polyhexamethylene guanidine (PHMG) has been extensively studied since the humidifier disinfectant incident. However, the impacts of inhalation of PHMG on the immune system are not comprehensively studied yet.
Zhengli YANG, Naimin SHAO, Yu DING, Jing XU, Junli LIU, Xi LIU, Kelei QIAN, Xinyu HONG   +7 more
doaj   +1 more source

Pesticide exposures and chronic kidney disease of unknown etiology: an epidemiologic review

Environmental Health, 2017
The main causes of chronic kidney disease (CKD) globally are diabetes and hypertension but epidemics of chronic kidney disease of unknown etiology (CKDu) occur in Central America, Sri Lanka, India and beyond.
Mathieu Valcke, Marie-Eve Levasseur, Agnes Soares da Silva, Catharina Wesseling   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source