Results 61 to 70 of about 15,665,920 (290)

Life cycle assessment as an analytical tool in strategic environmental assessment. Lessons learned from a case study on municipal energy planning in Sweden

open access: yes, 2012
Life cycle assessment (LCA) is explored as an analytical tool in strategic environmental assessment (SEA), illustrated by case where a previously developed SEA process was applied to municipal energy planning in Sweden.
Anna Björklund, Björklund, Anna,
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Tiering strategic environmental assessment and project environmental impact assessment in highway planning in Sao Paulo, Brazil

open access: yes, 2008
Constructing highways in dense urban areas is always a challenge. In Sao Paulo Metropolitan Region, heavy truck traffic contributes to clog streets and expressways alike.
Sanchez, Luis Enrique   +1 more
core   +1 more source

Inhibitory effect and mechanism of herbicide flurochloridone on osteogenic differentiation

open access: yesShanghai yufang yixue
ObjectiveTo explore the role of flurochloridone (FLC) on osteogenic differentiation and the potential mechanism of inhibiting bone formation, and to provide new insights into bone health risks associated with FLC pesticide exposure.MethodsNeonatal rat ...
XUE Liming   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Integrated Multi-Omics Links Bisphenol AF (BPAF) Exposure to Hepatic Lipid Metabolism Disruption via Succinate Dehydrogenase Dysfunction and Mitochondrial Impairment

open access: yesMetabolites
Background/Objective: Bisphenol AF (BPAF), a fluorinated analogue of bisphenol A, is an environmental contaminant associated with hepatotoxicity and metabolic disruption.
Ning Wang   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Towards Appraising the Impact of Legume Research [PDF]

open access: yes, 2023
This Impact Brief (No 44) is based on the Legumes Synthesis Report (http://impact.cgiar.org/sites/default/files/pdf/Legumes_Pachico-2014.pdf) that documents the most important cases of farmers adopting new varieties, and the economic, social and ...
CGIAR Standing Panel on Impact Assessment
core   +1 more source

Probing the binding stability of organic UV filters to human SLC transporters using AlphaFold and molecular dynamics simulations

open access: yesScientific Reports
The ubiquitous presence of organic ultraviolet filters (UVFs) in environmental and human, driven by their heavy usage in personal care formulations, has raised significant concern.
Ruikai Xing   +7 more
doaj   +1 more source

Effectes of perfluorooctanoic acid exposure on mouse embryonic osteoblast precursor cells and its molecular mechanisms

open access: yesShanghai yufang yixue
ObjectiveTo explore the biological mechanism of bone loss caused by perfluorooctanoic acid (PFOA) through transcriptomic analysis, and to provide new insights into regulating perfluoroalkyl substances (PFAS) applications and the prevention of hazards ...
XUE Liming   +5 more
doaj   +1 more source

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