Results 181 to 190 of about 2,717,832 (296)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Environmental Impact Assessment of Reusable and Disposable Surgical Head Covers.

open access: yesJAMA Surg, 2023
Cohen ES   +6 more
europepmc   +1 more source

Mainstreaming Flora Conservation Strategies into the Mitigation Hierarchy to Strengthen Environmental Impact Assessment. [PDF]

open access: yesEnviron Manage, 2023
Fernandes TN   +5 more
europepmc   +1 more source

Meteorological assessment of SRM exhaust products' environmental impact [PDF]

open access: yes
The environmental impact of solid rocket motor (SRM) exhaust products discharged into the free air stream upon the launching of space vehicles that depend upon SRM boosters to obtain large thrust was assessed.
Dingle, A. N.
core   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

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