Results 61 to 70 of about 5,624,280 (251)

Integration of Neutrosophic Logic and the PROMETHEE TODIM Method [PDF]

Neutrosophic Sets and Systems
The project was conducted in the Ashigua páramo, Mulaló, Latacunga, Cotopaxi province. Its objective was to develop a composite environmental sustainability indicator for the conservation of the páramo.
Patricio Clavijo Cevallos
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Ecological Footprint Policy? Land Use as an Environmental Indicator

, 2014
Summary: This article argues that policies aimed at sustainability need to address the spatial dimensions of environmental problems and their solutions.
van den Bergh, J.C.J.M., Grazi, F.
core   +1 more source

Characterization of acoustic traits and seasonal calling pattern of Dryophytes japonicus rain calls: a potential bioindicator of climate change

Journal of Ecology and Environment
Amphibians are sensitive to environmental change owing to their permeable skin and ectothermic nature. Frog calls can serve as bioindicators because call features and calling activity vary according to environmental factors.
Jiho Park, Jongsun Kim, Jiyeon Chun, Sung-Ryong Kang, Daesik Park   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Environmental Sustainability in Practice

, 2017
1. Introduction: What is Environmental Sustainability?2. Sustainability Education3. Environmental Planning and Management4. Sustainable Agriculture5. Geospatial Technologies and Environmental Sustainability6.
Environmental Sustainability Research Centre
core   +1 more source

What Factors can Influence the Expansion of Protected Areas around the World in the Context of International Environmental and Development Goals?

Problemy Ekorozwoju, 2018
The protection of biodiversity is an integral part of sustainable development. All the major international environmental and development programs – Aichi Biodiversity Targets, Millennium Development Goals and Sustainable Development Goals – have ...
Zdeněk Opršal, Jaromír Harmáček, Petr Pavlík, Ivo Machar   +3 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source