Results 71 to 80 of about 1,493,909 (303)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Indicators: tools for informing, monitoring or controlling? [PDF]
, 2015 Today, indicators are produced and used worldwide; across all levels and sectors of society; by public, private and civil society actors; for a variety of purposes, ranging from knowledge-provision to administrative control. While the use of quantitative
Lehtonen, Markku
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
NATURAL BIODEGRADATION OF COPROSTANOL IN AN EXPERIMENTAL SYSTEM OF THREE ENVIRONMENTAL CONDITIONS OF JAKARTA WATERS, INDONESIA [PDF]
, 2004 Constraint of using bio-indicator (coliform bacteria) as an indicator of domestic (sewage) pollution in the environment with high environmental stress encourages the discovering of other alternate indicators.
Bachtiar, Tonny +2 more
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Systematizing Environmental Indicators and Indices
Journal of Environment and Ecology, 2014 Environmental indicators and indices are detailed and complex devices that attempt to describe not only ecological status but also the reactions of the biosphere to the demands placed on it by society. Researchers have proposed the use of hundreds of different environmental indicators to evaluate everything from socially responsible investing, to the ...
openaire +2 more sources
Top management team and board attributes and firm performance in the Netherlands [PDF]
, 1999 We survey the evidence on the relationship between board and top management team attributes and firm performance in the Netherlands (sample of 94 listed firms).
Ees, Hans van, +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Environmental health indicators
, 2004 This presentation gives a general overview of the project titled Environmental Health Indicators, coordinated by WHO and managed by the Research Centre on the Toxic Oil Syndrome and Rare Diseases in Spain. The presentations describes the objectives of the project, the steps taken and the results obtained during the feasibility study.
Posada de la Paz, Manuel +2 more
+6 more sources