Results 111 to 120 of about 21,210,125 (249)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Method of choosing soils as CEB or pavement layers based on geological and environmental information and mode of treatment. [PDF]

MethodsX, 2023
Ilalie MKB, Véronique KKB, Valentine KY, Armand W, Paul NJ, Désiré NP, Antoine E.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Delegation of Administrative Authority and Responsibility for Information Assurance, Security, and Awareness

, 2008
Information ...
Information Technology
core  

A New and Flexible Architecture for the German Environmental Information Network

, 2005
Since the year 2000, the German Environmental Information Network gein® provides access to government-owned environmental information of 15 German federal states and the German federal government.
Klenke, Martin, Vögele, homas, Groschupf, Stefan, Kruse, Fred   +3 more
core   +1 more source

Components of a stock market transparency measurement model: a literature review

Accounting and Management Research
Transparency is the principle under which the stock market operates; a transparent organization is more likely to attract investors and thus to manage its costs and generate value.
Otilia Miladys Gil Hoyos, Yanni Gabriel Guacaneme Álvarez, Nadeska Gallardo Licháa   +2 more
doaj   +1 more source

Stakeholders' perspectives and use of web-based knowledge support for environmental information on pharmaceuticals. [PDF]

Explor Res Clin Soc Pharm, 2023
Linder E, Villén J, Nekoro M, Wettermark B, Sporrong SK.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Reply to Muzzioli et al.: Communicating nutrition and environmental information to food system stakeholders. [PDF]

Proc Natl Acad Sci U S A, 2023
Clark M, Springmann M, Rayner M, Scarborough P, Hill J, Tilman D, Macdiarmid JI, Fanzo J, Bandy L, Harrington RA.   +9 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source