Results 121 to 130 of about 5,439,350 (296)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A multifaceted purpose-oriented approach to evaluate material circularity index for rejuvenated recycled asphalt mixtures

Scientific Reports
This study investigates the impact of different mechanical properties, test procedures, and environmental and economic factors on the Material Circularity Index (MCI) of rejuvenated recycled asphalt mixtures.
Masood Gholami, Ali Khodaii, Pouria Hajikarimi   +2 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Neurotoxicity in complex environmental mixtures-a case-study at River Danube in Novi Sad (Serbia) using zebrafish embryos. [PDF]

Environ Sci Pollut Res Int, 2023
Massei R, Brack W, Seidensticker S, Hollert H, Muz M, Schulze T, Krauss M, Küster E.   +7 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Machine learning-based estimation of CO2 footprint and environmental-mechanical performance of blended cement concrete

Case Studies in Construction Materials
Blended cements with supplementary cementitious materials (SCMs) are extensively used to mitigate the environmental impact of concrete. However, assessing their environmental performance often requires detailed data and time-intensive analyses.
Felipe Vargas, Iván La Fé-Perdomo, Jorge A. Ramos-Grez, Ivan Navarrete   +3 more
doaj   +1 more source

Experimental evolution of herbicide resistance in chlamydomonas reinhardtii [PDF]

Our understanding of the evolutionary dynamics of selection for herbicide resistance is limited by the time and space required to conduct meaningful selection experiments in higher plants. This constrains the study of the
Lagator, Mato
core  

Environmental toxicity of complex chemical mixtures [PDF]

, 2009
Complex chemical mixtures may be released into the environment from a variety of sources including hazardous waste sites. Components of chemical mixtures and their metabolites may be genotoxic leading to cancer and heritable gene mutations.
Gillespie, Annika Margaret
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Transportation-related Environmental Mixtures and Diabetes Prevalence and Control in Urban/Metropolitan Counties in the United States. [PDF]

J Endocr Soc, 2023
Weiss MC, Adusumilli S, Jagai JS, Sargis RM.   +3 more
europepmc   +1 more source