Results 141 to 150 of about 5,439,350 (296)

Investigation of deformation characteristics of asphalt mixtures containing Reclaimed Asphalt Pavement (RAP) binders using laboratory simulations

open access: yesHybrid Advances
Asphalt pavement deterioration, particularly in developing countries such as Nigeria, has led to a significant increase in waste asphalt, presenting environmental and sustainability challenges.
Idorenyin Ndarake Usanga   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Multi-criteria assessment of recycled polyethylene terephthalate (PET) incorporation in bituminous mixtures: application to the cameroonian context

open access: yesTransportation Research Interdisciplinary Perspectives
The valorization of plastic waste in road construction represents a promising solution to both environmental and infrastructure challenges in developing countries. This study investigates the mechanical, economic, and environmental performance of asphalt
Timothée Thierry Odi Enyegue   +8 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Use of Steel Slag Aggregates and Recycled Crumb Rubber in Stone Mastic Asphalt (SMA) for High-Capacity Road Pavements

open access: yesBuildings
Stone Mastic Asphalt (SMA) mixtures are widely used in high-capacity road pavements due to their durability and resistance to permanent deformation. However, although electric arc furnace (EAF) steel slag and recycled crumb rubber have been individually ...
José Manuel Baraibar   +5 more
doaj   +1 more source

Double trouble: The synergistic threat of environmental stressors and pesticide mixtures

open access: yesJournal of Hazardous Materials
Journal of hazardous materials 500, 140293 (2025).
Naeem Shahid   +6 more
openaire   +4 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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