Results 91 to 100 of about 10,565,206 (325)

A Scoping Review of Technological Approaches to Environmental Monitoring

International Journal of Environmental Research and Public Health, 2020
Indoor environment quality (IEQ) can negatively affect occupant health and wellbeing. Air quality, as well as thermal, visual and auditory conditions, can determine how comfortable occupants feel within buildings.
G. Coulby, A. Clear, O. Jones, A. Godfrey   +3 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Polar Environmental Monitoring [PDF]

The present and projected benefits of the polar regions were reviewed and then translated into information needs in order to support the array of polar activities anticipated.
Nagler, R. G., Schulteis, A. C.
core   +1 more source

Hyperspectral Imaging in Environmental Monitoring: A Review of Recent Developments and Technological Advances in Compact Field Deployable Systems

Italian National Conference on Sensors, 2019
The development and uptake of field deployable hyperspectral imaging systems within environmental monitoring represents an exciting and innovative development that could revolutionize a number of sensing applications in the coming decades.
M. B. Stuart, A. McGonigle, J. Willmott
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Environmental lobbying with imperfect monitoring of environmental quality [PDF]

In this paper we present a two stage game of political lobbying for policies designed to enhance environmental quality. Unlike previous work which has tended to assume perfect monitoring of environmental quality in lobbying games we allow for imperfect ...
Beard, Rodney, Mallawaarachchi, Thilak, Salerno, Gillian   +2 more
core   +1 more source

A review of Indigenous knowledge and participation in environmental monitoring

, 2020
There is a growing interest by governments and academics in including Indigenous knowledge alongside scientific knowledge in environmental management, including monitoring.
Kim‐Ly Thompson, T. Lantz, Natalie Ban
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The corresponding countermeasures of landslide risk control under influence of climate change in China

Geomatics, Natural Hazards & Risk
As one of the most landslide-prone countries, China is significantly affected by climate change worldwide. Understanding the influences of climate change on landslides and optimizing the corresponding countermeasures cannot be overstated. In this article,
Bin Tong, Yixiang Zhang, Gan Qi, Jusong Shi, Yuanqiang Wan, Jianyin He, Xudong Yang   +6 more
doaj   +1 more source