Results 51 to 60 of about 612,879 (280)

Assessing Geomorphological Changes and Oil Extraction Impacts in Abandoned Yellow River Estuarine Tidal Flats Using Cloud Coverage in Region of Interest (CCROI) and WDM

Applied Sciences
Waterline extraction is a key step in applying the Waterline Detection Method (WDM) to Digital Elevation Model (DEM) generation. Cloud interference remains a major challenge for achieving high-quality extraction of waterlines.
Lianjie Zhang, Jishun Yan, Pan Zhang, Bo Zhao, Xia Lin, Quanming Wang   +5 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Radioactive Level in Fishes and Surface Sediments from the Coastal Areas of Nuclear Power Plants

Haiyang Kaifa yu guanli, 2022
To evaluate the effects of operating nuclear power plants on the ecological environment in the surrounding sea areas, 4 nuclear power plants which had been operated along the coast of China, namely Tianwan Nuclear Power Plant, Qinshan Nuclear Power Plant,
Yu KE, Xianggen LIU, Saizhang TAN, Tao YANG, Yuanzhou HUANG, Tianqi WEI, Xiaoshan JIANG   +6 more
doaj  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Distribution and Long-Term Variation of Wetland Land Cover Types in the Yellow River Delta Remote Sensing Monitoring

Journal of Marine Science and Engineering
Wetlands are dubbed the “kidneys of the earth” and are involved in climate regulation, carbon sequestration, ecological balance preservation, and reducing the surface water pollution.
Chao Zhou, Qian Zhao, Tong Wu, Xulong Liu, Yanlong Chen   +4 more
doaj   +1 more source

Distribution Characteristics of Environmental Factors and Eutrophication Assessment in the Yancheng Coastal Areas

Haiyang Kaifa yu guanli, 2023
Spatial and temporal variations of nutrients and COD in the coastal waters of Yancheng coastal areas were studied based on three seasonal cruises during 2018.
Haihua XU, Yanzhe DING, Lihua LI, Yuheng ZHANG, Chengjuan CAO, Zhongwei CHEN, Lingxiao HANG, Xuyu ZHU   +7 more
doaj  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Multi-model Evaluation and Bayesian Model Averaging in Quantitative Air Quality Forecasting in Central China

Aerosol and Air Quality Research, 2022
There has been much interest in air pollution and the forecasting skill of air quality models in China since winter 2013. Different air quality models use different parameters (e.g., meteorological fields, emission sources and the initial concentrations ...
Haixia Qi, Shuangliang Ma, Jing Chen, Junping Sun, Lingling Wang, Nan Wang, Weisi Wang, Xiefei Zhi, Hao Yang   +8 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source