Results 61 to 70 of about 676,874 (258)

Quantifying semi-volatile organic contaminants in solution by internal standard addition method requires prompt addition of the internal standards

open access: yesScientific Reports, 2020
The precision and accuracy of quantifying semi-volatile organic compounds (SVOCs) in solution by GC/MS, particularly when volume errors are unpredictable or difficult to control, are improved by utilizing internal standards (IS).
Ochan Otim, Jesus Rocha
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Radioactive Level in Fishes and Surface Sediments from the Coastal Areas of Nuclear Power Plants

open access: yesHaiyang Kaifa yu guanli, 2022
To evaluate the effects of operating nuclear power plants on the ecological environment in the surrounding sea areas, 4 nuclear power plants which had been operated along the coast of China, namely Tianwan Nuclear Power Plant, Qinshan Nuclear Power Plant,
Yu KE   +6 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Distribution Characteristics of Environmental Factors and Eutrophication Assessment in the Yancheng Coastal Areas

open access: yesHaiyang Kaifa yu guanli, 2023
Spatial and temporal variations of nutrients and COD in the coastal waters of Yancheng coastal areas were studied based on three seasonal cruises during 2018.
Haihua XU   +7 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Distribution and Long-Term Variation of Wetland Land Cover Types in the Yellow River Delta Remote Sensing Monitoring

open access: yesJournal of Marine Science and Engineering
Wetlands are dubbed the “kidneys of the earth” and are involved in climate regulation, carbon sequestration, ecological balance preservation, and reducing the surface water pollution.
Chao Zhou   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy