Results 51 to 60 of about 2,493,169 (277)

Integrating multiple sensor modalities for environmental monitoring of marine locations [PDF]

, 2008
In this paper we present preliminary work on integrating visual sensing with the more traditional sensing modalities for marine locations. We have deployed visual sensing at one of the Smart Coast WSN sites in Ireland and have built a software ...
Diamond, Dermot, O'Connor, Edel, O'Connor, Noel E., Smeaton, Alan F.   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Polystyrene Nanoplastics Elicit Multiple Responses in Immune Cells of the Eisenia fetida (Savigny, 1826)

Toxics
The improper disposal of plastic products/wastes can lead to the release of nanoplastics (NPs) into environmental media, especially soil. Nevertheless, their toxicity mechanisms in soil invertebrates remain unclear.
Huijian Shi, Yaoyue Wang, Xiangxiang Li, Xiaoyang Wang, Yuntao Qi, Shaoyang Hu, Rutao Liu   +6 more
doaj   +1 more source

Quantifying semi-volatile organic contaminants in solution by internal standard addition method requires prompt addition of the internal standards

Scientific Reports, 2020
The precision and accuracy of quantifying semi-volatile organic compounds (SVOCs) in solution by GC/MS, particularly when volume errors are unpredictable or difficult to control, are improved by utilizing internal standards (IS).
Ochan Otim, Jesus Rocha
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Ambient Rivers and Shellfish Tissue Monitoring in New Hampshire Estuarine Watersheds 2003 [PDF]

, 2004
The Department of Environmental Services received funding from the New Hampshire Estuaries Project (NHEP) to conduct monitoring activities in 2003. The activities involved water monitoring in tidal tributaries and contaminant analyses of mussel tissue ...
Landry, Natalie, Trowbridge, Phil
core   +1 more source

Assessing, valuing and protecting our environment- is there a statistical challenge to be answered? [PDF]

, 2013
This short article describes some of the evolution in environmental regulation, management and monitoring and the information needs, closely aligned to the statistical challenges to deliver the evidence base for change and ...
Gemmell, J. Campbell, Scott, E. Marian
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Assessing Geomorphological Changes and Oil Extraction Impacts in Abandoned Yellow River Estuarine Tidal Flats Using Cloud Coverage in Region of Interest (CCROI) and WDM

Applied Sciences
Waterline extraction is a key step in applying the Waterline Detection Method (WDM) to Digital Elevation Model (DEM) generation. Cloud interference remains a major challenge for achieving high-quality extraction of waterlines.
Lianjie Zhang, Jishun Yan, Pan Zhang, Bo Zhao, Xia Lin, Quanming Wang   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source