Results 51 to 60 of about 838,496 (307)

Early warning monitoring and risk assessment on heavy metals in Shangba drinking water source in Nanjing

open access: yes上海师范大学学报. 自然科学版, 2013
Heavy metal changes in Shangba drinking water source of Nanjing had been studied since the end of 2012 to the first of 2013, based on the analysis on continuous automatic monitoring data for Hg, As, Cu, Pb and Cd.
FU Yin, LIU Jun, CHEN Cheng, FANG Dong
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Dugong (Dugong dugon) Conservation in China: Current Status, Challenges, and Policy Recommendations

open access: yesConservation
The dugong (Dugong dugon) is the sole extant species of the genus Dugong within the order Sirenia, and the only strictly herbivorous marine mammal. As one of the oldest marine mammals, it plays a vital role in maintaining marine biodiversity.
Yue Zhang   +5 more
doaj   +1 more source

Development of environmental effects monitoring protocol in Brazil: a fish guide study of three river estuaries

open access: yes, 2019
In Brazil, there are no unified and effective environmental monitoring models for bodies of water. Thus, several methodologies are used that result in information that is often difficult to compare, especially for stakeholders involved in regional water ...
Reis Filho, Ricardo Wagner   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Polystyrene Nanoplastics Elicit Multiple Responses in Immune Cells of the Eisenia fetida (Savigny, 1826)

open access: yesToxics
The improper disposal of plastic products/wastes can lead to the release of nanoplastics (NPs) into environmental media, especially soil. Nevertheless, their toxicity mechanisms in soil invertebrates remain unclear.
Huijian Shi   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Quantifying semi-volatile organic contaminants in solution by internal standard addition method requires prompt addition of the internal standards

open access: yesScientific Reports, 2020
The precision and accuracy of quantifying semi-volatile organic compounds (SVOCs) in solution by GC/MS, particularly when volume errors are unpredictable or difficult to control, are improved by utilizing internal standards (IS).
Ochan Otim, Jesus Rocha
doaj   +1 more source

Ambient Lakes Monitoring Network: Panel 1; Volume 1 of 2

open access: yes, 2008
The New Jersey Department of Environmental Protection (NJDEP) initiated a renewed ambient lake monitoring network in 2005. This renewed initiative was undertaken by Water Monitoring & Standards' (WM&S) Bureau of Freshwater & Biological Monitoring (BFBM).

core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy