Results 91 to 100 of about 492,382 (314)

Analisis Kemampuan Memecahkan Permasalahan Lingkungan dan Ekoliterasi Siswa

open access: yes, 2019
The purpose of this study was to determine the ability of students to solve environmental problems through ecoliteration. The research method used in this study was a 2 x 2 factorial design experiment.
Nadiroh
core   +1 more source

Adaptive Sea Clutter Suppression for Marine Radar Systems to Enhance Uncrewed Surface Vehicle Autonomy

open access: yesNavigation
Marine radar is crucial for detecting objects near ships and ensuring safe navigation, and the performance of marine radar relies heavily on gain-tuning.
Seongpil Cho, Jae Yong Lee, Jungwook Han
doaj   +1 more source

Local and Global Sensitivity Analysis of Cr (VI) Geogenic Leakage Under Uncertain Environmental Conditions

open access: yesWater Resources Research, 2018
We focus on the joint application of local and global sensitivity analyses to characterize propagation of model parameter uncertainties to outputs of subsurface water geochemical models.
G. Ceriotti   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Bioprocess Convergence Using Sentinel Genes for Process Parameter Tuning

open access: yes, 2011
In vitro cell culture is a vital part of therapeutic biomolecule, cell therapy and vaccine production. In order to assure product identity, safety, potency and efficacy, controlled manufacturing processes are essential.
Kondragunta, Bhargavi
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

COMPARISON OF THERMAL COMFORT PARAMETERS USING DIFFERENT FEATURE SELECTION ALGORITHMS

open access: yesEskişehir Osmangazi Üniversitesi Mühendislik ve Mimarlık Fakültesi Dergisi
This study aims to examine the environmental parameters affecting user thermal comfort in an amphitheater belonging to an educational building and to compare the effects of these parameters using different feature selection algorithms.
Resul Özlük, Türkan Göksal Özbalta
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Environmental organochlorines and semen quality: Results of a pilot study

open access: yes, 2002
There have been numerous studies that suggest that sperm concentrations (sperm counts) are declining in men. However, other studies suggest that sperm counts are not declining or may be increasing in some areas.
Schiff, I   +13 more
core   +1 more source

Home - About - Disclaimer - Privacy