Results 31 to 40 of about 285,119 (237)

Touba-Mbacké, un "îlot vert urbain" dans le Sahel sénégalais ? Mode d'insertion et usages de la végétation dans la deuxième agglomération sénégalaise

Physio-Géo
The article examines the growth of woody vegetation in the agglomeration of Touba-Mbacké, which is marked by a very strong demographic and economic dynamism. It is studied by remote sensing between 1973 (period of rainfall deficit) and 2024.
Moctar Diouf
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Measuring China’s Policy Stringency on Climate Change for 1954–2022

Scientific Data
Efforts on climate change have demonstrated tangible impacts through various actions and policies. However, a significant knowledge gap remains: comparing the stringency of climate change policies over time or across jurisdictions is challenging due to ...
Bo Li, Enxian Fu, Shuhao Yang, Jiaying Lin, Wei Zhang, Jian Zhang, Yaling Lu, Jiantong Wang, Hongqiang Jiang   +8 more
doaj   +1 more source

Análisis del sistema de protección ambiental de la Costa del Sol. Una frontera en litigio entre el espacio litoral y su trasfondo montañoso

Cybergeo, 2003
This paper analyses Protected Natural Spaces Net that have been marked in the Malaga Costa del Sol and the mountain background. We try to find if the aim of this environmental planning figures is the result of a functional net adapted to the natural ...
José Gómez Zotano, Antonia Paniza Cabrera   +1 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Litter origins, accumulation rates, and hierarchical composition on urban roadsides of the Inland Empire, California

Environmental Research Letters, 2022
Urban areas are the primary source of human-made litter globally, and roadsides are a primary accumulation location. This study aimed to investigate how litter arrives at roadsides and determine the accumulation rate and composition of roadside litter ...
Win Cowger, Andrew Gray, Hannah Hapich, Jasmine Osei-Enin, Salvador Olguin Jr, Britney Huynh, Hinako Nogi, Samiksha Singh, Stanley Brownlee, Jonathan Fong, Trevor Lok, Gideon Singer, Hoori Ajami   +12 more
doaj   +1 more source

Promotion of Ecological Civilization Construction in the Pearl River Delta Region

中国工程科学, 2022
Ecological civilization construction is a major national development strategy. Studying the empirical modes and promotion strategies of ecological civilization construction in economically developed regions is vital for leading the construction across ...
Wang Jinnan, Jiang Hongqiang, Wu Wenjun, Liu Nianlei, Duan Yang, Wang Mingxu   +5 more
doaj   +1 more source