Results 51 to 60 of about 2,152,746 (305)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
GIS and remote sensing techniques to plan environmental linear parks [PDF]
Revista Brasileira de Cartografia, 2006 In the linear parks bibliography most of the case studies show that park planning is done based on its history and particular attributes, without a methodology that can guide new projects.
Lucilia do Carmo Giordano +1 more
doaj
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
FY13 Planning Task Force Documents: University Library System, University of Pittsburgh, August 2011-June 2012 [PDF]
, 2012 These documents provide a record of the work of the ULS FY13 Planning Task Force, which initiated and deployed a highly inclusive strategic planning process to analyze the library's strategic options, prioritize them, and identify key actions for ...
Arroyo-Ramirez, Elvia M +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Reclamações ambientais em Aveiro, Portugal: atores, preocupações, padrão territorial e resoluções [PDF]
, 2009 This paper presents an environmental diagnosis based on public complaints on environmental issues submitted to the Environmental Department of the Aveiro City Council, Portugal, between 2000 and 2005.
Carvalho, Daniela, Fidélis, Teresa
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Town of Chester Stormwater Management Project [PDF]
, 2008 Great Bay Environmental Consulting (GBEC) worked with the Town of Chester Planning Board to improve regulatory approaches to stormwater management.
NHEP Community Technical Assistance Program
core +2 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source