Results 61 to 70 of about 2,152,746 (305)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

North Slope Borough water study: a background for planning [PDF]

open access: yes, 1977
The Planning and Research Section of Alaska Dept. of Natural Resources initiated this pilot water study with the North Slope Borough and the University of Alaska's Arctic Environmental Information and Data Center and Institute of Water Resources ...
Dreyer, Linda Dwight, Johnson, Ronald A.
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Masdar - The Sustainable Desert City: A Theoretical Mirage or A Realistic [PDF]

open access: yes, 2010
Masdar City, currently being developed in Abu Dhabi and designed by Foster + Partners, a high-profile British firm of architects, sets a groundbreaking example of a new breed of eco-cities. The city’s birth has taken on an environmental stance. Having
Tang, Gabriel
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Community Essay: EPA's P3 - People, Prosperity, and Planet - Award

open access: yesSustainability: Science, Practice, & Policy, 2005
The United States Environmental Protection Agency (USEPA) has launched a unique grant program called P3 (People, Prosperity and the Planet), to foster future generations of scientists, engineers, and technology workers who can advance the principles of ...
Julie Beth Zimmerman
doaj  

Geospatial Decision Support for Forest Trail Constructions Allocation Using GIS-Network Analysis and Hybrid MADM Methods (AHP–PROMETHEE II)

open access: yesGeographies
Effective forest trail planning requires objective and transparent tools to balance user accessibility, recreation quality, and environmental protection.
Georgios Kolkos
doaj   +1 more source

Planning for ecological connectivity across scales of governance in a multifunctional regional landscape

open access: yesEcosystems and People, 2019
Although a landscape is a single environmental system, human systems of governance at the landscape scale are often fragmented across jurisdictions and diverse stakeholders, impeding coordinated planning to maintain ecological connectivity.
Lael Parrott   +4 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Ecoestructura y funcionalidad del espacio agrourbano [PDF]

open access: yesCiudades, 2009
The Guadalfeo’s Vega belonging to the Granada’s Province is a Mediterranean litoral heritage under pressure during the last decades due to the planned and unplanned growth of urban and touristic land uses.
Luis Miguel Valenzuela Montes   +2 more
doaj  

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