Results 41 to 50 of about 7,151,732 (291)

Reflections on Foucauldian Discource Analysis in Planning and Environmental Research [PDF]

open access: yes, 2001
YesDiscourse analysis is becoming an increasingly common approach in planning and environmental policy research. This paper asserts that the generic treatment of discourse analysis obscures distinct approaches where `discourses¿ can combine different ...
Sharp, Liz, Richardson, T.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Análisis del sistema de protección ambiental de la Costa del Sol. Una frontera en litigio entre el espacio litoral y su trasfondo montañoso

open access: yesCybergeo, 2003
This paper analyses Protected Natural Spaces Net that have been marked in the Malaga Costa del Sol and the mountain background. We try to find if the aim of this environmental planning figures is the result of a functional net adapted to the natural ...
José Gómez Zotano   +1 more
doaj   +1 more source

A more-than-human approach to environmental planning

open access: yes, 2019
This chapter presents a more-than-human approach to environmental planning, which proceeds from a fundamentally relational understanding of human nature.
Jonathan Metzger, Metzger, Jonathan,
core   +1 more source

THE IMPACT OF ACTOR-RELATIONAL DYNAMICS ON INTEGRATED PLANNING PRACTICE [PDF]

open access: yes, 2021
Integrated planning processes involve an increasing number of actors and aim to create synergy between multiple knowledges in communicative settings. Planning research has acknowledged that the actor-relational aspects of planning processes are not yet ...
Mladenović, Miloš N.   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Litter origins, accumulation rates, and hierarchical composition on urban roadsides of the Inland Empire, California

open access: yesEnvironmental Research Letters, 2022
Urban areas are the primary source of human-made litter globally, and roadsides are a primary accumulation location. This study aimed to investigate how litter arrives at roadsides and determine the accumulation rate and composition of roadside litter ...
Win Cowger   +12 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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