Results 51 to 60 of about 2,131,774 (334)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Litter origins, accumulation rates, and hierarchical composition on urban roadsides of the Inland Empire, California

open access: yesEnvironmental Research Letters, 2022
Urban areas are the primary source of human-made litter globally, and roadsides are a primary accumulation location. This study aimed to investigate how litter arrives at roadsides and determine the accumulation rate and composition of roadside litter ...
Win Cowger   +12 more
doaj   +1 more source

Promotion of Ecological Civilization Construction in the Pearl River Delta Region

open access: yes中国工程科学, 2022
Ecological civilization construction is a major national development strategy. Studying the empirical modes and promotion strategies of ecological civilization construction in economically developed regions is vital for leading the construction across ...
Wang Jinnan   +5 more
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Mapeamento para o zoneamento ecológico do território de Alagoas, Brasil.

open access: yesConfins, 2019
This article reports on the main natural segments of the Alagoan territory and presents a rational technique that portrays the landscape in a comprehensive sectoral drawing, based on topology.
Ajibola Isau Badiru   +3 more
doaj   +1 more source

Masdar - The Sustainable Desert City: A Theoretical Mirage or A Realistic [PDF]

open access: yes, 2010
Masdar City, currently being developed in Abu Dhabi and designed by Foster + Partners, a high-profile British firm of architects, sets a groundbreaking example of a new breed of eco-cities. The city’s birth has taken on an environmental stance. Having
Tang, Gabriel
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Planning for ecological connectivity across scales of governance in a multifunctional regional landscape

open access: yesEcosystems and People, 2019
Although a landscape is a single environmental system, human systems of governance at the landscape scale are often fragmented across jurisdictions and diverse stakeholders, impeding coordinated planning to maintain ecological connectivity.
Lael Parrott   +4 more
doaj   +1 more source

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