Results 61 to 70 of about 1,975,305 (345)
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Engenharia Agrícola, 2010 A Lei Federal 10.257, de 10 de julho de 2001, regulamentou os artigos 182 e 183 da Constituição Federal de 1988 no que trata da política urbana, especialmente da propriedade, sendo obrigatório para municípios com mais de 20.000 habitantes.
Gilberto J. Garcia +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
4D BIM for Construction Planning and Environmental Planning [PDF]
E3S Web of Conferences, 2019 In order to develop an algorithm for selecting the most optimal organizational and technical solutions during design process, and the following automatization of this process, the problem of using 4D modeling programs in the organization and technology of construction is considered.
Svetlana Sheina +3 more
openaire +3 more sources
Wind Turbines In The Landscape: Final Report & Script [PDF]
, 1994 The aim of this project was to produce a video film where the visual impact issues associated with current UK wind farms are addressed. The video is targeted to an audience of planners, planning committee members, planning consultants, environmental ...
Cook, T, Robotham, AJ
core +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti +5 more
wiley +1 more source
O uso da Avaliação Ambiental Estratégica nas decisões sobre cultivares transgênicos no Brasil
Desenvolvimento e Meio Ambiente, 2015 The environmental use of transgenic crops is controversial, due to the uncertainties regarding the potential environmental, social and economic impacts that may arise. In order to regulate the decisions on the use of genetically modified organisms (GMOs)
Denise Gallo Pizella +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source
The role of local ecological knowledge in sustainable urban planning: perspectives from Finland
Sustainability: Science, Practice, & Policy, 2005 This paper is a study of the role of local ecological knowledge (LEK) as lay-expert knowledge in the urban land use planning process in Finland . The research addresses the importance of LEK, and the ways LEK is obtained and used.
Johanna Kohl, Vesa Yli-Pelkonen
doaj