Results 71 to 80 of about 9,036,130 (408)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Tabular cusum control charts of chemical variables applied to the control of surface water quality Cartas de controle cusum tabular de variáveis químicas aplicadas ao controle de qualidade de águas superficiais

Engenharia Agrícola, 2012
The aim of this study was to evaluate the application possibility of tabular CUSUM control charts in the quality control of chemical variables in surface water. It was performed bibliographic and field research to collect water samples from 2003 to 2009,
Franciele A. C. Follador, Márcio A. Vilas Boas, Marlise Schoenhals, Eliane Hermes, Clovis Rech   +4 more
doaj   +1 more source

4D BIM for Construction Planning and Environmental Planning [PDF]

E3S Web of Conferences, 2019
In order to develop an algorithm for selecting the most optimal organizational and technical solutions during design process, and the following automatization of this process, the problem of using 4D modeling programs in the organization and technology of construction is considered.
Svetlana Sheina, Nikita Saltykov, Viktor Krikunov, Ekaterina Seraya   +3 more
openaire   +3 more sources

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

O uso de geotecnologias no planejamento ambiental: o plano diretor municipal de Tambaú - SP The use of geotechnologies in the environmental planning: the municipal masterplan of Tambaú-SP

Engenharia Agrícola, 2010
A Lei Federal 10.257, de 10 de julho de 2001, regulamentou os artigos 182 e 183 da Constituição Federal de 1988 no que trata da política urbana, especialmente da propriedade, sendo obrigatório para municípios com mais de 20.000 habitantes.
Gilberto J. Garcia, Sergio dos A. F. Pinto, Sergio L. Antonello, Mayra F. Nobre   +3 more
doaj   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Ngā mahi: Kaupapa Māori outcomes and indicators kete [PDF]

, 2009
As part of the Planning Under Cooperative Mandates research (PUCM) we developed a kaupapa Māori outcomes and indicators framework. This framework reflects tikanga Māori and Māori values. It also considers issues (including environmental issues) according
Jefferies, Richard, Kennedy, Nathan
core   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Environmental planning for an Alaskan water-oriented recreational area [PDF]

, 1978
Completion Report OWRT Agreement No. 14-31-0001-4056 Project No. B-026-ALASThis research focused initially on delineation of the proper procedures to be applied when the state of Alaska, through the appropriate agencies, selects and develops water ...
LaPerriere, Jacqueline Doyle
core  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source