Results 111 to 120 of about 354,848 (254)

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

Advanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai, Mingchao Zhang, Le Liu, Lide Tao, Chenyang Xu, Hao Chai, Xin Shi, Yin Wang, Xiaopei Zhang, Qiong Chen, Dong Liu, Jinyu Bai, Chang She, Xiaozhong Zhou, Cong Cao, Huajian Shan   +15 more
wiley   +1 more source

Perceptions of change in the environment caused by the COVID-19 pandemic: Implications for environmental policy. [PDF]

Environ Impact Assess Rev, 2023
Hidalgo-Triana N, Picornell A, Reyes S, Circella G, Ribeiro H, Bates AE, Rojo J, Pearman PB, Vivancos JMA, Nautiyal S, Brearley FQ, Pereña J, Ferragud M, Monroy-Colín A, Maya-Manzano JM, Ouachinou JMAS, Salvo-Tierra AE, Antunes C, Trigo-Pérez M, Navarro T, Jaramillo P, Oteros J, Charalampopoulos A, Kalantzi OI, Freitas H, Ščevková J, Zanolla M, Marrano A, Comino O, Roldán JJ, Alcántara AF, Damialis A.   +31 more
europepmc   +1 more source

Heuristically Adaptive Diffusion‐Model Evolutionary Strategy

Advanced Science, EarlyView.
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl, Yanbo Zhang, Hananel Hazan, Michael Levin   +3 more
wiley   +1 more source

Analytical method to derive environmental policy effects in an endogenous growth model with leisure. [PDF]

MethodsX, 2022
Hamaguchi Y, Bhuiyan MA, Rahman MK.
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

The Effect of Environmental Policy Uncertainty on Enterprises' Pollution Emissions: Evidence from Chinese Industrial Enterprise. [PDF]

Int J Environ Res Public Health, 2022
Le D, Ren F, Tang Y, Zhu Y.
europepmc   +1 more source

An Increasing Misalignment Between Crop Distribution and Environmental Resources Under Climate Change in China

Advanced Science, EarlyView.
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su, Zhentao Zhang, Jin Zhao, Xia Liang, Chuang Zhao, Zhijuan Liu, Minghao Zhuang, Jing Sun, Bo Lu, Ke Liu, Johannes W. M. Pullens, Matthew T. Harrison, Deli Chen, Xiaoguang Yang   +13 more
wiley   +1 more source

Revealing the effectiveness of environmental policy stringency and environmental law on environmental performance: does asymmetry matter? [PDF]

Environ Sci Pollut Res Int, 2022
Chen M, Sohail S, Majeed MT.
europepmc   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

The Impact of Environmental Technology and Environmental Policy Strictness on China's Green Growth and Analysis of Development Methods. [PDF]

J Environ Public Health, 2022
Wu Y, Zhang Y.
europepmc   +1 more source