Results 51 to 60 of about 1,691,175 (341)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Effects of land uses and slope gradients on soil physicochemical properties in Woynwha watershed, Northwest Ethiopia

open access: yesAgrosystems, Geosciences & Environment
Soil quality degradation has become a major problem that results in low agricultural productivity and increasing food insecurity in sub‐Saharan Africa. Improving our understanding of how different land uses and slope positions affect soil properties is ...
Workineh Ejigu Mesfin   +4 more
doaj   +1 more source

Nilai Ekonomi Jasa Penyerbukan pada Perkebunan Kopi Robusta

open access: yesJurnal Ilmu Lingkungan
Lebah berkontribusi terhadap pasokan makanan global sebagai penyerbukan berbagai tanaman, termasuk hortikultura, tanaman pangan, dan lainnya. Keberadaan lebah dan fungsinya sebagai penyerbuk menghadapi banyak tantangan seperti perubahan iklim dan teknik ...
Nuraulia Asyifa   +2 more
doaj   +1 more source

Clustering simulated snow profiles to form avalanche forecast regions [PDF]

open access: yesGeoscientific Model Development
This study presents a statistical clustering method that allows avalanche forecasters to explore patterns in simulated snow profiles. The method uses fuzzy analysis clustering to group small regions into larger forecast regions by considering snow ...
S. Horton   +3 more
doaj   +1 more source

Isotopes in hydrology and hydrogeology [PDF]

open access: yes, 2019
The structure, status, and processes of the groundwater system, which can only be acquired through scientific research efforts, are critical aspects of water resource management. Isotope hydrology and hydrogeology is a genuinely interdisciplinary science.
Barbieri, Maurizio
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

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