Results 81 to 90 of about 525,778 (258)
Staphylococcus aureus utilizes environmental RNA as a building material in specific polysaccharide-dependent biofilms. [PDF]
NPJ Biofilms Microbiomes, 2022 Chiba A +5 more
europepmc +1 more source
Dnmt2 in RNA methylation, RNA inheritance, and environmental responses in the mouse [PDF]
, 2016 Dnmt2 is a highly conserved RNA methyltransferase that is responsible for cytosine-C5 methylation of C38 in the anticodon-loop of tRNAAspGUC, tRNAValAAC, and tRNAGlyGCC. This modification has been shown to contribute to tRNA integrity and function. Additionally, it was demonstrated that RNA-mediated inheritance in mice depends on the presence of Dnmt2.
openaire +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Synergistic action of the gut microbiota in environmental RNA interference in a leaf beetle. [PDF]
Microbiome, 2021 Xu L +6 more
europepmc +1 more source
Potential roles of noncoding RNAs in environmental epigenetic transgenerational inheritance [PDF]
Molecular and Cellular Endocrinology, 2014 "Epigenetic transgenerational inheritance" (ETI) has been defined as germline (sperm or egg) transmission of epigenetic information between generations in the absence of direct exposures or genetic manipulations. Among reported cases of ETI in mammals, the majority are induced by environmental factors, including environmental toxicants [e.g ...
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
RNA silencing response in chloroplast-replicating viroid siRNA biogenesis in plants
Phytopathology ResearchRNA silencing represents a cellular regulatory and defence mechanism in eukaryotes across kingdoms. In plants, a combined functionality of DCL2 and DCL3 is crucial for their synergistic defence against whilst DCL4 is required for nucleus-replicating ...
Pengcheng Zhang +7 more
doaj +1 more source
Environmental perturbations lead to extensive directional shifts in RNA processing
PLOS Genetics, 2017 Abstract Environmental perturbations have large effects on both organismal and cellular traits, including gene expression, but the extent to which the environment affects RNA processing remains largely uncharacterized. Recent studies have identified a large number of genetic variants associated with variation in RNA processing that also
Allison L. Richards +7 more
openaire +5 more sources
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
An Isothermal Deoxyribozyme Sensor for Rapid Detection of Enteroviral RNA
BiosensorsEnteric viruses are a major cause of waterborne infections due to their high environmental stability and extremely low infectious dose. Current molecular diagnostic methods, while accurate, often depend on thermal cycling and centralized laboratory ...
Begüm Şaş +7 more
doaj +1 more source