Results 71 to 80 of about 892,996 (295)

RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response

Life Science Alliance, 2022
Comparative RNA interactome capture identifies potential regulators of RNA metabolism in fission yeast and reveals RNA exosome–dependent buffering of stress-responsive gene expression networks.
Adrien Birot, Krzysztof Kus, Emily Priest, Ahmad Al Alwash, Alfredo Castello, Shabaz Mohammed, Lidia Vasiljeva, Cornelia Kilchert   +7 more
doaj   +1 more source

Cold Induction of EARLI1, a Putative Arabidopsis Lipid Transfer Protein, Is Light and Calcium Dependent [PDF]

, 2004
As sessile organisms, plants must adapt to their environment. One approach toward understanding this adaptation is to investigate environmental regulation of gene expression.
Comai L., Gleave A.P., Henriksson K.N., Lee I., Murashige T., Sambrook J., Sukumaran N.P., Wang H., Wirtz K.W.   +8 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers

Nature Communications
Current clinical strategies for the delivery of pulmonary therapeutics to the lung are primarily targeted to the upper portions of the airways, such as treatment with nebulized instillation and inhalation.
Jaclynn A. Meshanni, Emily R. Stevenson, Dapeng Zhang, Rachel Sun, Nathan A. Ona, Erin K. Reagan, Elena Abramova, Chang-Jiang Guo, Melissa Wilkinson, Ishana Baboo, Yuzi Yang, Liuyan Pan, Devendra S. Maurya, Virgil Percec, Yongsheng Li, Andrew Gow, Drew Weissman, Elena N. Atochina-Vasserman   +17 more
doaj   +1 more source

Exploring nucleo-cytoplasmic large DNA viruses in Tara Oceans microbial metagenomes [PDF]

, 2013
Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of their unicellular hosts or by causing diseases in animals. To better characterize the
Acinas, Silvia G., Bork, Peer, Claverie, Jean-Michel, Clerissi, Camille, de Vargas, Colomban, Department of Applied Biological Sciences (DBIT), Vrije Universiteit Brussel, Brussels, Belgium, Department of Applied Biological Sciences (DBIT), Vrije Universiteit Brussel, Brussels, Belgium, Department of Applied Biological Sciences (DBIT), Vrije Universiteit Brussel, Brussels, Belgium, Desdevises, Yves, Faust, Karoline, Ferrera, Isabel, Grimsley, Nigel, Hingamp, Pascal, Jaillon, Olivier, Kandels-Lewis, Stefanie, Karsenti, Eric, Lima-Medez, Gipsi, Moreau, Hervé, Not, Fabrice, Ogata, Hiroyuki, Pesant, Stéphane, Poulain, Julie, Raes, Jeroen, Sarmento, Hugo, Subirana, Lucie, Sunagawa, Shinichi, Villar, Emilie, Wincker, Patrick   +27 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Dynamics and Functions of Stress Granules and Processing Bodies in Plants

Plants, 2020
RNA granules, such as stress granules and processing bodies, can balance the storage, degradation, and translation of mRNAs in diverse eukaryotic organisms.
Geng-Jen Jang, Jyan-Chyun Jang, Shu-Hsing Wu   +2 more
doaj   +1 more source

A Role for Pre-mRNA-PROCESSING PROTEIN 40C in the Control of Growth, Development, and Stress Tolerance in Arabidopsis thaliana [PDF]

, 2019
Because of their sessile nature, plants have adopted varied strategies for growing and reproducing in an ever-changing environment. Control of mRNA levels and pre-mRNA alternative splicing are key regulatory layers that contribute to adjust and ...
Careno, Daniel Alejandro, de Leone, María José, García Hourquet, Mariano, Hernando, Carlos Esteban, Iserte, Javier Alonso, Mora Garcia, Santiago, Yanovsky, Marcelo Javier   +6 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Microbial residence time is a controlling parameter of the taxonomic composition and functional profile of microbial communities. [PDF]

, 2019
A remaining challenge within microbial ecology is to understand the determinants of richness and diversity observed in environmental microbial communities.
Achermann, Stefan, Fenner, Kathrin, Johnson, David R, Joss, Adriano, Mansfeldt, Cresten, Men, Yujie, Villez, Kris, Walser, Jean-Claude   +7 more
core   +3 more sources