Results 41 to 50 of about 7,694,143 (305)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Developmental and toxicological effects of butylated hydroxytoluene metabolites on zebrafish larvae
Scientific ReportsButylated hydroxytoluene (BHT) is among the most widely used synthetic phenolic antioxidants. However, BHT and its metabolites have been detected in aquatic ecosystems, posing potential risks to aquatic organisms.
Won Noh +6 more
doaj +1 more source
Risk Analysis of Transporting Hazardous Substances in Harbor Using Modeling Program
한국해양공학회지, 2018 Recently, the use of hazardous chemicals has been continuously increasing. Therefore, the international trade volume is growing and chemical accidents have increased. Nowadays, the safety awareness of the public has increased. As a result, the management
Sukyoung Yoon +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Status and Assessment Method of Nuclear Safety Analysis Software in China
Frontiers in Energy Research, 2021 In recent years, China’s nuclear power industry has enjoyed a good momentum of development, and related companies have also developed many nuclear analysis software applications.
Xinli Gao +12 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 1994 Provides local environmental news and tips. Spring/Summer 1992 issue discusses lawn care, recycling, pesticides, and has a quiz. Spring/Summer 1993 discusses utility line clearing, lawn care, and car care.Prepared with a grant from the New Jersey ...
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Journal of Analytical Science and TechnologyBifenazate is a widely used insecticide for mite control and readily oxidizes to bifenazate-diazene, which can revert to bifenazate under mild reducing conditions.
Deuk-Yeong Lee +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source