Results 61 to 70 of about 7,694,143 (305)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Buckling suppression of a cantilever structure with a modified fuzzy sliding mode control

Scientific Reports
Based on fuzzy sliding mode control, a control strategy is developed for the buckling suppression of a cantilever structure. Due to the laminated composite structure, shear effects on the dynamic behavior of the structure are incorporated into the ...
Jianhua Pan, Lin Sun, Xiaopei Liu, Yuyuan Zhang, Yili Duo   +4 more
doaj   +1 more source

ENVIRONMENTAL RISK ASSESSMENT UNDER ENVIRONMENTAL STANDARD AND SAFETY-FIRST CONSTRAINTS [PDF]

The uncertainty weather condition could pose some challenge in achieving environmental target. In this study, we use a bioeconomic model to calculate the impacts of alternative management systems. Under different safety-first constraints on the levels of
Renck, Ashley Wood, Hite, Diane, Intarapapong, Walaiporn   +2 more
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Environmental behavior and the degradation of tire-rubber-related pollutant 6PPD-quinone in soils

Applied Biological Chemistry
N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q), a transformation product of the tire rubber antioxidant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine, has recently been identified as a contaminant of emerging concern due to its ...
Min-Young Kim, Ji-Young An, Deuk-Yeong Lee, Seong-Hoon Jeong, Jong-Hwan Kim   +4 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Validation of the UB-ROSC Score for Predicting OHCA Survival in Chiayi City, Taiwan

Emergency Medicine International
Out-of-hospital cardiac arrest (OHCA) is a critical public health issue, with survival rates varying widely due to multiple well-established factors, including emergency medical service (EMS) system structure, bystander response, initial cardiac rhythm ...
Wei Ta Chang, Chung Chyi Chou, Chia-Chou Tsai   +2 more
doaj   +1 more source

Assessment of combined risk to pesticide residues through dietary exposure

EFSA Journal, 2019
Plant protection products (PPPs) are preparations intended to protect plants and their products including one or more active substances. The use of PPPs may cause direct or indirect risks.
French Agency for Food, Environmental and Occupational Health & Safety (ANSES), France, Regulated Products Assessment Department, Residues and Food Safety Unit, E Chatzidimitriou, A Mienne, S Pierlot, L Noel, X Sarda   +5 more
doaj   +1 more source