Results 121 to 130 of about 11,919,473 (381)

The wave climate and its seasonal variability in the northeastern Baltic Sea [PDF]

open access: yesEstonian Journal of Earth Sciences, 2010
The basic features of wave properties in the Baltic Sea and their seasonal variations are estimated by the use of a high-resolution version (3 miles) of the wave model, WAM, driven by adjusted geostrophic winds for 1970–2007 under ice-free conditions ...
Räämet, Andrus, Soomere, Tarmo
doaj  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Collectively, we need to accelerate Arctic specimen sampling

open access: yesArctic Science, 2017
Natural history collections are not often thought of as observatories, but they are increasingly being used as such to observe biological systems and changes within them.
Kevin Winker, Jack Withrow
doaj   +1 more source

Relevant environmental science [PDF]

open access: yesEnvironmental Toxicology and Chemistry, 2003
Raymond C. Loehr, Peter M. Chapman
openaire   +3 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Moray eels are more common on coral reefs subject to higher human pressure in the greater Caribbean

open access: yesiScience, 2021
Summary: Proximity and size of the nearest market (‘market gravity’) have been shown to have strong negative effects on coral reef fish communities that can be mitigated by the establishment of closed areas.
Gina M. Clementi   +20 more
doaj  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy