Results 61 to 70 of about 1,521,759 (254)

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Where to restore: Connectivity forest for spatial prioritization in forest landscape restoration

iScience
Summary: Forest loss, fragmentation, and transformation negatively impact forest biodiversity and ecosystem functionality worldwide. Improving landscape intactness and connectivity through restoration is critical.
Xiaoming Wang, Johan Svensson, Bengt Gunnar Jonsson, Navinder J. Singh, Jakub W. Bubnicki, Andrés Lopéz-Peinado, Per Angelstam, Grzegorz Mikusiński, Jonas Ardö   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Disparities in ambient air pollution exposure among the U.S. population amid climate change

iScience
Summary: Air pollution and climate change remain critical environmental challenges. Using integrated modeling (global change analysis model [GCAM] and TM5-FASST), we assess future U.S.
Fatemeh Ganji, Jon Sampedro, Lu Liu, Yue Qin, Yuyu Zhou, Neal Graham, Gokul Iyer   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

PanAfrican Journal of Governance and Development (Full Issue)

PanAfrican Journal of Governance and Development, 2020
The PanAfrican Journal of Governance and Development (PJGD) is a peer-reviewed biannual, multi-, inter-, and trans-disciplinary journal that publishes editorials, articles, essays, book reviews, commentaries and notes on issues related to democracy, good
Center For PanAfrican Journal of Governance and Development
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Heterogeneous impacts of fear and policy on building energy use during COVID-19 in South Korea

iScience
Summary: The COVID-19 pandemic created a unique natural experiment in energy consumption, fundamentally reshaping demand. We analyzed electricity use in over one million South Korean buildings across six functional categories (May 2020 to April 2022 ...
Jonghyun Yoo, Daewon Kim, Minjung Kim
doaj   +1 more source