Results 81 to 90 of about 1,521,759 (254)

Effect of copper and cultivation condition on the transport, metabolism, and potential risk of tolfenpyrad in pea seedlings (Pisum sativum Linn.)

iScience
Summary: Pesticides and heavy metals are two major classes of environmental pollutants, and their environmental fate requires careful assessment.
Wenhao Xiong, Qin Tang, Yayong Xia, Sanfei Du, Jing Shi, Kankan Zhang   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Impact of mycotoxins and glyphosate residue on the gut microbiome and resistome of European fallow deer

iScience
Summary: Some mycotoxins and herbicide residues pose threats to animal health. These toxins might affect the gut microbiome of fallow deer. The analyzation of the intestinal content samples of this valuable game species exposed to varying levels of ...
Adrienn Gréta Tóth, Sára Ágnes Nagy, István Lakatos, Norbert Solymosi, Anikó Stágel, Melinda Paholcsek, Katalin Posta, Patrik Gömbös, Szilamér Ferenczi, Zsuzsanna Szőke   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Altitude-dependent climate impacts and economic feasibility of alternative fuels in aviation from 2025 to 2050

iScience
Summary: The aviation industry plays an increasing role in climate change due to emissions at cruise altitudes. This study combines projections from the Aviation Integrated Model (AIM) and simulations from the Aviation-FAIR model to assess greenhouse gas
Qiang Cui, Xu-jie Sun, Xing-yu Tang, Ying Zhou, Yu-xin Zhang, Ye Li   +5 more
doaj   +1 more source

Runoff estimation in residencial area

Revista Ambiente & Água, 2013
This study aimed to estimate the watershed runoff caused by extreme events that often result in the flooding of urban areas. The runoff of a residential area in the city of Guaratinguetá, São Paulo, Brazil was estimated using the Curve-Number method ...
Meire Regina de Almeida Siqueira, Paulo José Maria Filho, Myriam de Fátima Laurindo de Seixas, Marcelo dos Santos Targa, Getulio Teixeira Batista, Nelson Wellausen Dias, Paulo Augusto Romera e Silva   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source