Results 81 to 90 of about 1,580,543 (254)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Use of virtual reality to engage undergraduate students in environmental field experiences

Future in Educational Research
Field‐based experiences enhance cognitive and affective skill sets of undergraduate students. Although field‐based learning is a highly effective pedagogical modality, it is not accessible to all students, necessitating the development and evaluation of ...
Elizabeth W. Stoner, Steven C. Salina, Erin M. Johnson, Elizabeth R. Whitman, Stephanie K. Archer, Brodie S. McPherson, Alexana Cranmer   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Making climate reanalysis and CMIP6 data processing easy: two “point-and-click” cloud based user interfaces for environmental and ecological studies

Frontiers in Environmental Science
Climate reanalysis and climate projection datasets offer the potential for researchers, students and instructors to access physically informed, global scale, temporally and spatially continuous climate data from the latter half of the 20th century to ...
James M. Lea, Robert N. L. Fitt, Stephen Brough, Stephen Brough, Georgia Carr, Jonathan Dick, Natasha Jones, Richard J. Webster   +7 more
doaj   +1 more source

PANGAEA - Data Publisher for Earth & Environmental Science. [PDF]

Sci Data, 2023
Felden J, Möller L, Schindler U, Huber R, Schumacher S, Koppe R, Diepenbroek M, Glöckner FO.   +7 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The protein corona from nanomedicine to environmental science. [PDF]

Nat Rev Mater, 2023
Mahmoudi M, Landry MP, Moore A, Coreas R.   +3 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source