Results 71 to 80 of about 1,521,759 (254)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Hail as a damage vector for renewable energy
iScienceSummary: Hundreds of thousands of wind turbines and billions of solar photovoltaic (PV) panels are operating worldwide. Reliability, power production and operations, and maintenance costs for these electricity generation sources depend on operating ...
Sara C. Pryor, Rebecca J. Barthelmie
doaj +1 more source
How Can Humanities Interventions Promote Progress in the Environmental Sciences?
Humanities, 2017 Environmental humanists make compelling arguments about the importance of the environmental humanities (EH) for discovering new ways to conceptualize and address the urgent challenges of the environmental crisis now confronting the planet.
Sally L. Kitch
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Urban forest plant diversity affects soil organic carbon by regulating functional genes in Nanning
iScienceSummary: Urban forests serve as reservoirs of soil organic carbon (SOC) within ecosystems and play a critical role in the carbon (C) cycle. However, the regulatory mechanisms underlying SOC dynamics across urbanization gradients in urban forests remain ...
Wei Zhou +6 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frontiers in Environmental Science, 2017 The present paper is a preliminary analysis of the funding, organizational culture, environmental, and innovation challenges that are currently faced by Environmental Research Infrastructures (ERI) and private enterprises working together.
Abad Chabbi +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source