Results 121 to 130 of about 1,477,177 (315)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Protocol for the removal of polyvinyl chloride microplastics from water using activated jute stick charcoal

STAR Protocols
Summary: We present a protocol to remove polyvinyl chloride-based microplastics (MPs) from aquatic environments using jute stick activated charcoal (JSAC) as an adsorbent.
Nur Alom, Tapati Roy, Tanny Sarkar, Md Rasel, Md Sanwar Hossain, Mamun Jamal   +5 more
doaj   +1 more source

The disconnect between researcher ambitions and reality in achieving impact in the Earth & Environmental Sciences - author survey. [PDF]

F1000Res, 2021
Kelly A, Gardner V, Gilbert A.
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Systems Development Program of the Coast and Geodetic Survey, Environmental Science Services Administration

, 1968
Edward M. MacCutcheon
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Protocol for low-cost quantification of microplastics through electrochemical impedance spectroscopy from aqueous matrices

STAR Protocols
Summary: We present a protocol to quantify microplastics (MPs) in aqueous matrices by analyzing the solution resistance (Rs) imparted by MPs using electrochemical impedance spectroscopy (EIS).
Almeenu Rasheed, Sovik Das
doaj   +1 more source

Microbial World: Recent Developments in Health, Agriculture and Environmental Sciences: An Annual Conference Organized by Association of Microbiologists of India and Indian Network for Soil Contamination Research. [PDF]

Indian J Microbiol, 2021
Dhingra GG, Saxena A, Nigam A, Hira P, Singhvi N, Anand S, Kaur J, Kaur J, Dua A, Negi V, Gupta V, Sood U, Kumar R, Lal S, Verma H, Verma M, Singh P, Rawat CD, Tripathi C, Talwar C, Nagar S, Mahato NK, Prakash O, Singh M, Kuhad RC, Singh Y, Lal B, Pabbi S, Singh N, Kalia VC, Lal R.   +30 more
europepmc   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source