Results 161 to 170 of about 1,477,177 (315)

Environmental Sciences Division. Annual progress report for period ending September 30, 1975

, 1976

openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Opening doors to physical sample tracking and attribution in Earth and environmental sciences. [PDF]

Sci Data
Damerow JE, Raia NH, Stanley V, Choe S, Borton MA, Byers N, Cassidy ER, Cholia S, Edmunds R, Forbes B, Forrest K, Goldman AE, Kunze J, Lafia S, Lehnert K, McIntyre-Redden M, Naples R, O'Ryan D, Parker C, Plomp E, Powers-McCormack B, Ramdeen S, Richard S, Thessen A, Thompson CW, Vieglais D, Vrouwenvelder K, Wood-Charlson EM, Wyborn L, Reddy TBK, Thomer AK.   +30 more
europepmc   +1 more source

Library Searching: Resources and Strategies, with Examples from the Environmental Sciences (Book Review)

, 1978
Deanne Holzberlein
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Mapping large bodies of research in environmental sciences: insights from compiling evidence on the recovery and reuse of nutrients found in human excreta and domestic wastewater. [PDF]

Environ Evid
Harder R.
europepmc   +1 more source

Computer program to plot isotherms in bodies of water. Environmental Sciences Division publication No. 1199

, 1978
Donald L. DeAngelis
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Preserving Natural Science Collections: Chronicle of Our Environmental Heritage [PDF]

, 1993
W. Donald Duckworth, Hugh H. Genoways, Carolyn L. Rose   +2 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Assessing semantic interoperability in environmental sciences: variety of approaches and semantic artefacts. [PDF]

Sci Data
Di Muri C, Pulieri M, Raho D, Muresan AN, Tarallo A, Titocci J, Nestola E, Basset A, Mazzoni S, Rosati I.   +9 more
europepmc   +1 more source