Results 171 to 180 of about 930,563 (304)

Ecology-based approach to predict no-effect antibiotic concentrations for minimizing environmental selection of resistance. [PDF]

ISME J
Kneis D, de la Cruz Barron M, Konyali D, Westphal V, Schröder P, Westphal-Settele K, Schönfeld J, Jungmann D, Berendonk TU, Klümper U.   +9 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Evidence of horizontal gene transfer and environmental selection impacting antibiotic resistance evolution in soil-dwelling Listeria. [PDF]

Nat Commun
Goh YX, Anupoju SMB, Nguyen A, Zhang H, Ponder M, Krometis LA, Pruden A, Liao J.   +7 more
europepmc   +1 more source

Genomic signatures of environmental selection despite near-panmixia in summer flounder. [PDF]

Evol Appl, 2018
Hoey JA, Pinsky ML.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Environmental selection and advective transport shape the distribution of two cyst-forming Acantharia clades in the Canadian Arctic. [PDF]

J Plankton Res
Thaler M, Labarre A, Lovejoy C.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Do Community Characteristics Determine Environmental Outcomes? Evidence from the Toxics Release Inventory [PDF]

This research uses neighborhood characteristics (at the zipcode level) to explain changes in toxic releases between 1990 and 1993. It combines the Toxics Release Inventory data with demographic data from the 1990 US Census.
Arora, Seema, Cason, Timothy
core  

Population Genomic Signatures of Genetic Structure and Environmental Selection in the Catadromous Roughskin Sculpin Trachidermus fasciatus. [PDF]

Genome Biol Evol, 2019
Li YL, Xue DX, Zhang BD, Liu JX.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source