Results 61 to 70 of about 2,198,845 (262)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

St. Catherines Island Flyover

open access: yesSouthern Spaces, 2015
In this peer-reviewed short video and essay, Steve Bransford, Anthony Martin, and Michael Page explore the history and terrain of St. Catherines Island, a privately owned barrier island along the Georgia Atlantic coast.
Steve Bransford   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

New Shades o'Death Creek

open access: yesSouthern Spaces, 2009
Denise Giardina evokes the physical and emotional landscapes of mountain top removal in this excerpt from her novel, Fallam's Secret.
Denise Giardina
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

"Aint that Something?"

open access: yesSouthern Spaces, 2016
Carter Sickels reviews Robert Gipe's illustrated novel Trampoline (Athens: Ohio University Press, 2015).
Carter Sickels
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Research Data Management in Environmental Studies: Scoping Review and Bibliometrics Analysis

open access: yesData Science Journal
This research attempts to analyse and reveal the scientific trends in research data management (RDM) related to environmental studies through the scoping review and bibliometric analysis.
Rosini   +3 more
doaj   +1 more source

ORGANIZING DATA FOR ENVIRONMENTAL STUDIES [PDF]

open access: yesEnvironmental Toxicology and Chemistry, 1982
Abstract Using the vapor pressure, water solubility and molecular weight of a chemical, the partitioning of that chemical between the major environmental compartments can be quickly assessed. Thus it is possible to estimate what percentage of the chemical will be located in the ground, bottom sediments, water and air.
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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