Results 41 to 50 of about 1,468,974 (264)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Sustainability Policy and Environmental Policy [PDF]
A representative agent economy with a resource stock, polluting emissions, productive, abatement and foreign capital, trade, and technical progress, is used to contrast environmental policy, which internalises amenity and productivity values, with ...
John C. V. Pezzey
core +3 more sources
Social-ecological systems approach in drought-food insecurity nexus research
npj Sustainable AgricultureDrought is increasingly seen as the next “pandemic,” threatening global populations and progress towards achieving zero hunger by 2030. Although drought and food security are well-researched, no studies synthesize the progress and gaps in drought-food ...
Debashis Roy +3 more
doaj +1 more source
Target proteins reprogrammed by As and As + Si treatments in Solanum lycopersicum L. fruit
BMC Plant Biology, 2017 Background Arsenic is an important contaminant of many arable soils worldwide, while silicon, one of the most abundant elements in the earth’s crust, interacts with As in the context of plant metabolism.
Marta Marmiroli +3 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Discover EnvironmentImproper solid waste management is one of the causes of environmental and health problems in many cities worldwide. It is in this context that the study aimed to determine the solid waste management strategies used in Amaveni suburbs in Kwekwe, Zimbabwe ...
Chireshe Amato +5 more
doaj +1 more source
COVID-19 pandemic-related changes in wellness behavior among older Americans
BMC Public Health, 2021 Background COVID-19 has taken its toll on citizens in all 50 states of the United States. The United States (U.S.) leads the world with 30,291,863 confirmed reported cases and 549,664 deaths as of March 29, 2021 compared to globally confirmed cases at ...
Elgloria Harrison +8 more
doaj +1 more source
Review: Solar Power innovation, sustainability, and environmental justice [PDF]
, 2020 revie
Lowe-Wincentsen, Dawn
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source