Results 81 to 90 of about 1,468,974 (264)

Environmental, human health and socio-economic effects of cement powders: The multicriteria analysis as decisional methodology [PDF]

, 2017
The attention to sustainability-related issues has grown fast in recent decades. The experience gained with these themes reveals the importance of considering this topic in the construction industry, which represents an important sector throughout the ...
Bellagamba, Simona, DI MASCIO, Paola, MORETTI, LAURA   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The potential role of safety, health, environmental quality (SHEQ) management systems in sustainable landfill management in Zimbabwe-a review

Discover Sustainability
Solid waste management is a demanding issue globally. Zimbabwe is among nations in Southern Africa that faces political and socio-economic challenges in solid waste management including landfill management. However, proper landfill management is critical
Steven Jerie, Tapiwa Shabani, Takunda Shabani, Amato Chireshe   +3 more
doaj   +1 more source

Petroleum Hydrocarbon Contamination in Terrestrial Ecosystems—Fate and Microbial Responses

Molecules, 2019
Petroleum hydrocarbons represent the most frequent environmental contaminant. The introduction of petroleum hydrocarbons into a pristine environment immediately changes the nature of that environment, resulting in reduced ecosystem functionality. Natural
Adam Truskewycz, Taylor D. Gundry, Leadin S. Khudur, Adam Kolobaric, Mohamed Taha, Arturo Aburto-Medina, Andrew S. Ball, Esmaeil Shahsavari   +7 more
doaj   +1 more source

Indicators and Evaluation Tools for the Assessment of Urban Sustainability [PDF]

This paper attempts to provide an explanation of why reductionistic approaches are not adequate to tackle the urban sustainability issue in a consistent way.
Giuseppe Munda
core  

An assessment tool and integrated index for sustainable oil palm production [PDF]

, 2010
Many prominent sectors of the international agricultural commodities market have been calling upon their stakeholders to define and implement social responsibility and sustainability benchmarks, aiming at product quality and production practices ...
Caliman, Jean-Pierre, Stachetti Rodrigues, Géraldo, Verwilghen, Aude   +2 more
core  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Implementing transit oriented development in Greater London [PDF]

, 2019
This book provides new dimensions and a contemporary focus on sustainable transport, urban regeneration and development in eight countries spanning four continents at different stages of development.
Papa, E., Papa, E.
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source