Results 41 to 50 of about 584,647 (289)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Sustainability of the chemical manufacturing industry - Towards a new paradigm? [PDF]

, 2010
This paper describes the current situation of the chemicalmanufacturingindustry, with special reference to Europe and looks to the future sustainability demands on the sector, and the implications of these demands for chemical engineering education ...
Allen, Allenby, American Chemistry Society, Aragon-Correa, Armstrong, Batterham, Benoit, Bucciarelli, Byrne, Clift, Coley, Curran, Cussler, Evans, Favre, Florida, Garcia-Serna, George M. Hall, Graedel, Harris, Hill, Joe Howe, Jorgensen, Judge, Kemp, Kuhn, Labuschange, Matus, McDonough, McGhee, Mitchell, Satterfield, Snow, World Commission on Environment and Development   +33 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Contextualizing Environmental Sustainability in Design Engineering Curricula [PDF]

Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, 2014
Consideration of environmental sustainability is significantly altering the nature of the mechanical design process. This necessitates integration of sustainability related learning content in design engineering curricula. Although various frameworks for teaching sustainable design exist, a survey conducted among practicing student engineers shows the ...
Devarajan Ramanujan, William Z. Bernstein, Monica Cardella, Karthik Ramani   +3 more
openaire   +1 more source

Raising awareness for potential sustainability effects in Uganda: A survey-based empirical study [PDF]

, 2019
Copyright © 2019 for this paper by its authors. In July 2019, we ran the 3rd International BRIGHT summer school for Software Engineering and Information Systems at the Makerere University in Kampala, Uganda.
Bainomugisha, E., Chaudron, M., Dearden, Andrew, Duboc, L., Hebig, R., Kanagwa, B., Okello, D., Penzenstadler, B., Umuhoza, E.   +8 more
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Environmental sustainability requirement specification levels for comprehensive requirements engineering

Cleaner Environmental Systems
The consideration of sustainability early in product development presents significant challenges for the field of mechanical engineering. Linking broad corporate strategies to specific product attributes such as dimensions and functions requires repeated,
Niklas Quernheim, Benjamin Schleich
doaj   +1 more source

Junkbots [PDF]

, 2013
The School of Science and Technology at the University of Northampton have been working with local schools to create robots made from junk and also to use robots programmed by the students to perform simple rubbish clearing exercises.
Turner, Scott J
core  

Green BPM as a business-oriented discipline : a systematic mapping study and research agenda [PDF]

, 2019
Green Business Process Management (BPM) focuses on the ecological impact of business processes. This article provides a systematic mapping study of Green BPM literature to evaluate five attributes of the Green BPM research area: (1) scope, (2 ...
Couckuyt, Dries, Van Looy, Amy
core   +1 more source