Results 41 to 50 of about 588,114 (308)

Contextualizing Environmental Sustainability in Design Engineering Curricula [PDF]

Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, 2014
Consideration of environmental sustainability is significantly altering the nature of the mechanical design process. This necessitates integration of sustainability related learning content in design engineering curricula. Although various frameworks for teaching sustainable design exist, a survey conducted among practicing student engineers shows the ...
Devarajan Ramanujan, William Z. Bernstein, Monica Cardella, Karthik Ramani   +3 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Environmental sustainability requirement specification levels for comprehensive requirements engineering

Cleaner Environmental Systems
The consideration of sustainability early in product development presents significant challenges for the field of mechanical engineering. Linking broad corporate strategies to specific product attributes such as dimensions and functions requires repeated,
Niklas Quernheim, Benjamin Schleich
doaj   +1 more source

Junkbots [PDF]

, 2013
The School of Science and Technology at the University of Northampton have been working with local schools to create robots made from junk and also to use robots programmed by the students to perform simple rubbish clearing exercises.
Turner, Scott J
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Raising awareness for potential sustainability effects in Uganda: A survey-based empirical study [PDF]

, 2019
Copyright © 2019 for this paper by its authors. In July 2019, we ran the 3rd International BRIGHT summer school for Software Engineering and Information Systems at the Makerere University in Kampala, Uganda.
Bainomugisha, E., Chaudron, M., Dearden, Andrew, Duboc, L., Hebig, R., Kanagwa, B., Okello, D., Penzenstadler, B., Umuhoza, E.   +8 more
core  

A review of the lighting performance in buildings through energy efficiency [PDF]

, 2014
As developing countries including Malaysia, are now moving towards sustainable development is in line with the Ninth Malaysia Plan, 9th MP, the development should be built to meet current and future needs for achieving sustainability of economic ...
Kamaruzzaman, S.N, Zulkifli, Nursyahida
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Current status and pillars of direct air capture technologies

iScience, 2022
Summary: Climate change calls for adaptation of negative emission technologies such as direct air capture (DAC) of carbon dioxide (CO2) to lower the global warming impacts of greenhouse gases.
Mihrimah Ozkan, Saswat Priyadarshi Nayak, Anthony D. Ruiz, Wenmei Jiang   +3 more
doaj   +1 more source