Results 41 to 50 of about 1,183,701 (265)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Digestion and Absorption of Dietary Phosphorus in Fish
FishesThe absorption of dietary phosphorus typically begins with the digestive phase, where various chemical processes take place. These include the solubilization of calcium phosphates by gastric acid in the stomach, as well as the enzymatic breakdown of ...
Shozo H. Sugiura
doaj +1 more source
Information and Communication Technology (ICT) and Environmental Sustainability in Developed and Developing Countries [PDF]
Pakistan Journal of Commerce and Social Sciences, 2018 This study conducts a comparative empirical analysis of 132 developed and developing economies to explore the links of ICT with environment over the period 1980-2016.
Muhammad Tariq Majeed
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Global warming, carbon cycles, forests and photosynthesis; a hypothesis for global cooling
Frontiers in Earth ScienceIn relation to global warming and the role of carbon dioxide, the atmospheric residence-time of carbon dioxide from industrial emissions, and the carbon dioxide fixation capacity by photosynthesis in forests, land areas and oceans is considered, for the ...
Jacob E. John
doaj +1 more source
Architectural technology for environmental design
Techne, 2011 The scientific field of «Architectural Technology» has long incorporated the discipline of «Environmental Design», by giving explicit visibility to already present embedded in its foundation.
Fabrizio Schiaffonati +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source