Results 51 to 60 of about 1,497,264 (313)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Climate vulnerability and green innovation: A cross-country analysis

Journal of Open Innovation: Technology, Market and Complexity
This study contributes to the growing literature on environmental innovation by offering novel cross-country evidence on how climate vulnerability shapes green innovation.
Nguyen T. Tran, Tung D. Nguyen, My Nguyen, Phuong M.H. Pham   +3 more
doaj   +1 more source

Innovative Energy and Environmental Technology Verification (EETV) Factsheet

, 2000
This document provides information regarding the Energy and Environmental Technology Verification (EETV) Program, the Verification/Certification Process, the role of the New Jersey Corporation for Advanced Technology, the three Tiers of the Technology ...

core   +1 more source

Environmental problems and technological opportunities [PDF]

Technological Forecasting and Social Change, 1986
Abstract The argument of this article is that environmental problems are a direct consequence of a certain Weltanschauung Christianism brought into Western societies. Fairly simple solutions exist for the large ecological problems generated by the intrusion of humanity in the ecosphere, including at the extreme an almost complete withdrawal ...
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Digestion and Absorption of Dietary Phosphorus in Fish

Fishes
The absorption of dietary phosphorus typically begins with the digestive phase, where various chemical processes take place. These include the solubilization of calcium phosphates by gastric acid in the stomach, as well as the enzymatic breakdown of ...
Shozo H. Sugiura
doaj   +1 more source

Putting environmental technologies into the mainstream: Adoption of environmental technologies by medium-sized manufacturing firms in Brazil [PDF]

Journal of Cleaner Production, 2017
The aim of this research is to analyze how critical success factors (CSFs) can influence the adoption of environmental technologies by Brazilian manufacturing companies. In terms of conceptual background, this research fits within the context of environmental management in corporate organizations, focusing on the adoption of environmental technologies ...
Diana, Gabriel Cepollaro, Jabbour, Charbel Jose Chiappetta, Jabbour, Ana Beatriz Lopes de Sousa, Kannan, Devika   +3 more
openaire   +7 more sources

Environmental sustainability: A technology acceptance perspective

International Journal of Information Management, 2022
Abstract Air and water pollution, resource depletion, soil erosion, consequent large-scale ecosystem changes and the threat of global warming have resulted in stakeholders becoming more attuned to the sustainability implications of new technologies. Information systems are no exception.
Savvas Papagiannidis, Davit Marikyan
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source