Results 61 to 70 of about 4,082,360 (307)

Bifurcation of environmental safety: Science and technology [PDF]

open access: yesE3S Web of Conferences
The paper analyzes the provisions of the domestic legislative base and legal doctrine on the discussion issues of substantive and essential parameters of the category of environmental safety of the state.
Lang Petr
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Environmental technology’s diminishing marginal returns: a study of green patents and emission reductions in China

open access: yesFrontiers in Environmental Science
IntroductionDo environmental technologies always yield desirable returns? This study addresses this question through the lens of command-and-control environmental regulation.
Xiaoyu Yin   +3 more
doaj   +1 more source

Environmental technology and a multiple approach of competitiveness

open access: yesFuture Business Journal, 2020
This paper investigates the relationships between environmental technology and competitiveness focusing on 224 industrial corporations. To date, there is still a debate regarding the benefits of being green.
Milad Abdelnabi Salem   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Unintended consequences of trade in environmental innovation: Agricultural emissions, sectoral leakage, and the Kuznets curve hypothesis

open access: yesAgricultural Economics (AGRICECON)
Mitigating emissions from the agricultural sector is crucial for achieving sustainable development goals. However, controlling emissions in one sector can lead to unintended consequences in others through leakage effects.
Xinyi Gu   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The limitations of speech control: perceptions of provision of speech-driven environmental controls [PDF]

open access: yes, 2011
This study set out to collect data from assistive technology professionals about their provision of speech-driven environmental control systems. This study is part of a larger study looking at developing a new speech-driven environmental control ...
Craig A   +5 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Linking Environmental Management Practices to Environmental Performance: The Interactive Role of Environmental Audit [PDF]

open access: yesPakistan Journal of Commerce and Social Sciences, 2020
Drawing on institutional theory using data of S&P 500 listed firms over the period 2007 to 2018, this study examines the role of external environmental audit between environmental management practices (EMP) and environmental performance. In particular,
Shoaib Aslam   +2 more
doaj  

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