Results 71 to 80 of about 1,183,701 (265)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Environmental technology’s diminishing marginal returns: a study of green patents and emission reductions in China

Frontiers in Environmental Science
IntroductionDo environmental technologies always yield desirable returns? This study addresses this question through the lens of command-and-control environmental regulation.
Xiaoyu Yin, Baofeng Xu, Jia Li, Jingyi Wu   +3 more
doaj   +1 more source

Bifurcation of environmental safety: Science and technology [PDF]

E3S Web of Conferences
The paper analyzes the provisions of the domestic legislative base and legal doctrine on the discussion issues of substantive and essential parameters of the category of environmental safety of the state.
Lang Petr
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Unintended consequences of trade in environmental innovation: Agricultural emissions, sectoral leakage, and the Kuznets curve hypothesis

Agricultural Economics (AGRICECON)
Mitigating emissions from the agricultural sector is crucial for achieving sustainable development goals. However, controlling emissions in one sector can lead to unintended consequences in others through leakage effects.
Xinyi Gu, Jianmin Li, Farzan Yahya, Muhammad Waqas, Amad Rashid   +4 more
doaj   +1 more source

Environmental technology and a multiple approach of competitiveness

Future Business Journal, 2020
This paper investigates the relationships between environmental technology and competitiveness focusing on 224 industrial corporations. To date, there is still a debate regarding the benefits of being green.
Milad Abdelnabi Salem, Fekri Shawtari, Hafezali Bin Iqbal Hussain, Mohd Farid Shamsudin   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Environmental regulation, technology density, and green technology innovation efficiency

Heliyon
From the perspective of the innovation value chain, this study divides the innovation efficiency of green technology into two stages: R&D efficiency and achievement transformation efficiency.
Pengzhen Liu, Tao Huang, Yueting Shao, Bin Jia   +3 more
doaj   +1 more source