Results 81 to 90 of about 17,196 (172)
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye +5 more
wiley +1 more source
Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman +3 more
wiley +1 more source
Effects of common environmental pollutants on sperm DNA methylation
Infertility is a common reproductive disorder affecting millions of couples worldwide. It is estimated that male factors account for about 30%-50% of infertility cases, and some studies have found that the concentration of male sperm gradually decreases ...
Xin GUO +5 more
doaj +1 more source
ABSTRACT Background Irish Travellers are a distinct minority ethnic group with a long tradition of nomadism on the island of Ireland. Travellers have a significantly reduced life expectancy and experience greater health inequalities. Limited evidence describes how cancer awareness and engagement with prevention, screening and early diagnosis are shaped
Kate Frazer +12 more
wiley +1 more source
Rhinitis is one of the most common respiratory diseases, influenced by various environmental factors such as green space, air pollution and indoor microbiomes. However, their interactions and combined effects have not been reported.
Liu Yang +7 more
doaj +1 more source
Associations between outdoor air pollution and cancers other than lung cancer remain unclear, particularly in the context of tobacco use. Here, the authors assessed possible links between ambient air pollutant exposure and incidence of 20 non‐lung cancers among adults followed over a 25‐year period in the United States.
W. Ryan Diver +4 more
wiley +1 more source
Over the last few years, investigating the changes of gut microbiota after the exposure to airborne pollution has gained increasing interest, due to the evidence that altered microbial communities may contribute to the development of chronic diseases.The
Simone Filardo +7 more
doaj +1 more source
Detection Techniques for Polycyclic Aromatic Hydrocarbons and Their Metabolites: A Review
Overview of the different techniques that can be used to detect polyclic aromatic hydrocarbons and their metabolites. Polycyclic aromatic hydrocarbons (PAHs) are a class of organic pollutants affecting the environment as well as individual health that has been linked to various diseases including cancer.
Martin Wolfgang Konrad +3 more
wiley +1 more source
ABSTRACT Chronic diseases are the leading causes of morbidity and mortality worldwide and impose a substantial and long‐lasting burden on individuals, families, communities, and healthcare systems. In Australia, more than 47% of the population had at least one chronic condition in 2018, and the prevalence rose sharply with age: approximately 80% of ...
Getahun Kebede Beyera
wiley +1 more source

