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Exploration of microRNA Biomarkers in Blood Small Extracellular Vesicles for Enzootic Bovine Leukosis [PDF]

Microorganisms, 2023
Enzootic bovine leukosis (EBL) is a B-cell lymphosarcoma caused by the bovine leukemia virus (BLV). While most infected cattle show no clinical signs, approximately 30% of infected cattle develop persistent lymphocytosis (PL), and a small percentage may ...
Akane Takada, Yuji O. Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima   +4 more
doaj   +5 more sources

Effect of C-to-T transition at CpG sites on tumor suppressor genes in tumor development in cattle evaluated by somatic mutation analysis in enzootic bovine leukosis [PDF]

mSphere
Oncogenic transformation of normal cells is caused by mutations and chromosomal abnormalities in cancer-related genes. Enzootic bovine leukosis (EBL) is a malignant B-cell lymphoma caused by bovine leukemia virus (BLV) infection in cattle.
Asami Nishimori, Kiyohiko Andoh, Yuichi Matsuura, Tomohiro Okagawa, Satoru Konnai   +4 more
doaj   +4 more sources

Current Developments in the Epidemiology and Control of Enzootic Bovine Leukosis as Caused by Bovine Leukemia Virus. [PDF]

Pathogens, 2020
Enzootic Bovine Leukosis (EBL) caused by the bovine leukemia virus (BLV) has been eradicated in over 20 countries. In contrast, the U.S. and many other nations are experiencing increasing prevalence in the absence of efforts to control transmission ...
Bartlett PC, Ruggiero VJ, Hutchinson HC, Droscha CJ, Norby B, Sporer KRB, Taxis TM.   +6 more
europepmc   +7 more sources

Identification of Potential mRNA Biomarkers in Milk Small Extracellular Vesicles of Enzootic Bovine Leukosis Cattle. [PDF]

Viruses, 2022
Enzootic bovine leukosis (EBL) is a disease caused by bovine leukemia virus (BLV); only a small percentage of BLV-infected cattle develop EBL and present with B-cell lymphosarcoma.
Hiraoka M, Takashima S, Wakihara Y, Kamatari YO, Shimizu K, Okada A, Inoshima Y.   +6 more
europepmc   +4 more sources

Serum bta-miRNA-375 as a potential biomarker for the early diagnosis of enzootic bovine leukosis. [PDF]

PLoS One
To identify a biomarker for the early diagnosis of enzootic bovine leukosis (EBL) caused by bovine leukemia virus (BLV), we investigated the expression of a microRNA, bta-miR-375, in cattle serum. Using quantitative reverse-transcriptase PCR analysis, we
Murakami K, Matsunaga T, Matsuzaki T, Naruke Y, Miyauchi S, Kobayashi S, Yoneyama S, Sakai Y, Ichijo T, Hirata TI, Kimura A, Chiba Y, Matsuda KI, Yamada S, Hikono H.   +14 more
europepmc   +4 more sources

Enzootic bovine leukosis in a 21-month-old Japanese Black cow with high susceptibility. [PDF]

J Vet Diagn Invest, 2022
A 21-mo-old Japanese Black beef cow had swollen mandibular and superficial cervical lymph nodes. Fine-needle aspiration cytology of the superficial cervical lymph node revealed large lymphoblasts with mitoses present.
Maezawa M, Sakaguchi K, Tagaino Y, Fujii Y, Akagami M, Kawakami J, Watanabe KI, Kobayashi Y, Ogawa H, Inokuma H.   +9 more
europepmc   +4 more sources

Time course changes in peripheral B-cell clonality in a Japanese Black bull with enzootic bovine leukosis. [PDF]

J Vet Med Sci, 2022
A 38-month-old Japanese Black bull presenting with anorexia was given supportive treatment without improvement. Findings including bovine leukemia virus positivity and monoclonal B-cell proliferation strongly suggested the onset of enzootic bovine ...
Maezawa M, Oouci Y, Akagami M, Uneyama M, Chambers JK, Uchida K, Inokuma H.   +6 more
europepmc   +4 more sources

Risk factors associated with enzootic bovine leukosis in Boyaca and Cundinamarca municipalities, Colombia [PDF]

Open Veterinary Journal, 2023
Background: Enzootic Bovine Leukosis (EBL) is a lymphoproliferative disorder caused by Bovine Leukemia Virus (BLV), a virus of the Retroviridae family.
Deisy Johana Lancheros-Buitrago, Diana Maria Bulla-Castañeda, Julio Cesar Giraldo-Forero, Martin Orlando Pulido-Medellin   +3 more
doaj   +3 more sources

A case-control study to elucidate factors contributing to the inability to stand in cattle with enzootic bovine leukosis based on postslaughter inspections. [PDF]

J Vet Med Sci
Enzootic bovine leukosis (EBL) can significantly impact herd productivity. This study aimed to elucidate the factors contributing to the inability of cattle with EBL to stand.
Yamamoto N, Kameda S, Genda K, Shinozuka Y, Hisaeda K, Inoue Y, Goto A.   +6 more
europepmc   +3 more sources

A clinical case of enzootic bovine leukosis in a Holstein cow with minor clonality of B-cell in the peripheral blood. [PDF]

J Vet Med Sci
A 4-year 9-month-old Holstein-Friesian dairy cow presented with anorexia. On physical examination, swelling of superficial lymph nodes, pelvic masses, and prolonged urination posture after urinating a small amount were noted.
Maezawa M, Kikuzawa M, Takiguchi A, Saito R, Chambers JK, Uchida K, Inokuma H.   +6 more
europepmc   +3 more sources